{"id":"syd-101-0-03","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL3663408","moleculeType":"Small molecule","molecularWeight":"411.48"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"SYD-101 is a novel antifungal compound formulated as a 0.03% topical preparation. It is being developed by Sydnexis for the treatment of fungal infections, likely targeting dermatophytes or other superficial fungal pathogens through disruption of fungal cell wall or membrane components.","oneSentence":"SYD-101 is a topical antifungal agent that disrupts fungal cell membrane integrity.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:36:59.736Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Fungal skin infections (specific indication under investigation in Phase 3)"}]},"trialDetails":[{"nctId":"NCT03918915","phase":"PHASE3","title":"The Safety and Efficacy of SYD-101 in Children With Myopia","status":"COMPLETED","sponsor":"Sydnexis, Inc.","startDate":"2019-04-24","conditions":"Nearsightedness, Near Sightedness, Near-sightedness","enrollment":852}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":267593,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["atropine sulfate"],"phase":"phase_3","status":"active","brandName":"SYD-101 0.03%","genericName":"SYD-101 0.03%","companyName":"Sydnexis, Inc.","companyId":"sydnexis-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"SYD-101 is a small molecule ophthalmic solution being studied for the treatment of myopia, or nearsightedness, in children. It is being tested in a clinical trial at concentrations of 0.01% and 0.03% compared to a vehicle control.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}