{"id":"supplemental-oxygen-therapy","safety":{"commonSideEffects":[{"rate":null,"effect":"Oxygen-induced hypoventilation (in CO₂ retainers)"},{"rate":null,"effect":"Dry airways and mucous membrane irritation"},{"rate":null,"effect":"Atelectasis (absorption atelectasis with high FiO₂)"},{"rate":null,"effect":"Oxygen toxicity (with prolonged high-concentration exposure)"},{"rate":null,"effect":"Discomfort from delivery device"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Supplemental oxygen works by delivering higher concentrations of oxygen than ambient air (21% O₂) directly to the patient's airways via various delivery devices (nasal cannula, mask, etc.). This increases the partial pressure of oxygen in the alveoli and enhances oxygen diffusion across the alveolar-capillary membrane, thereby raising arterial oxygen saturation and improving oxygen delivery to tissues. 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