{"id":"sulfasymazine","rwe":[],"tags":[{"label":"sulfasymazine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"symasul","offLabel":[],"synonyms":["sulfasymazine","prosymasul","sulphsymazine","symasul"],"timeline":[],"approvals":[],"brandName":"Symasul","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"sulfasymazine","explanation":"Think of it like a nutrient that bacteria need to grow. Symasul blocks the production of this nutrient, making it difficult for bacteria to multiply and cause infection. This helps the body's immune system fight off the infection more effectively.","oneSentence":"Symasul works by inhibiting the synthesis of folic acid in bacteria, which is essential for their growth and replication.","technicalDetail":"Symasul is a sulfonamide antimicrobials that acts as a competitive inhibitor of dihydropteroate synthase, an enzyme involved in the synthesis of tetrahydrofolate, a precursor to folic acid."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3836","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=SULFASYMAZINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:45:52.656958","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:02:38.838892+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[],"genericName":"sulfasymazine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"ZZZ3BU4OA7","CHEBI":"CHEBI:135305","INN_ID":"1097","UMLSCUI":"C0075526","ChEMBL_ID":"CHEMBL2107230","PUBCHEM_CID":"16132","MESH_SUPPLEMENTAL_RECORD_UI":"C005744"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":13,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Symasul (SULFASYMAZINE) is a small molecule drug in the sulfasymazine class. Its original development is not specified, and its current owner is also unknown. The target and indications for Symasul are not provided. It is unclear if Symasul is FDA-approved or off-patent, and its commercial status is unknown. Further information on its pharmacokinetics, such as half-life and bioavailability, is also unavailable.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T11:02:38.838892+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}