{"id":"sulfaguanole","rwe":[],"tags":[{"label":"sulfaguanole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"enterocura","offLabel":[],"synonyms":["sulfaguanole","enterocura","sulfaguanol"],"timeline":[],"approvals":[],"brandName":"Enterocura","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"sulfaguanole","explanation":"Think of it like a key that fits into a lock. The bacteria have special locks that help them make proteins and grow. Enterocura is like a key that blocks these locks, preventing the bacteria from making the proteins they need to survive and multiply.","oneSentence":"Enterocura works by inhibiting bacterial enzymes, disrupting the bacteria's ability to carry out essential functions.","technicalDetail":"As a sulfaguanole, Enterocura is believed to act as a competitive inhibitor of bacterial enzymes, specifically targeting the enzyme dihydropteroate synthetase, which is essential for the synthesis of folic acid and other vital compounds in bacteria."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2506","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=SULFAGUANOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:44:44.400866","biosimilars":[],"competitors":[],"genericName":"sulfaguanole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"0X9P7B60UD","CHEBI":"CHEBI:135318","INN_ID":"2874","UMLSCUI":"C0601952","ChEMBL_ID":"CHEMBL2107223","PUBCHEM_CID":"9571041","MESH_SUPPLEMENTAL_RECORD_UI":"C003900"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Infectious Disease"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Enterocura is a small molecule medication. It is also known by the synonyms Sulfaguanol and Sulfaguanole.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}