{"id":"succinylsulfathiazole","rwe":[{"pmid":"35978220","year":"2022","title":"In-line sample concentration in capillary electrophoresis by cyclodextrin to admicelle microextraction.","finding":"","journal":"Analytical and bioanalytical chemistry","studyType":"Clinical Study"},{"pmid":"33957263","year":"2021","title":"Succinylsulfathiazole modulates the mTOR signaling pathway in the liver of c57BL/6 mice via a folate independent mechanism.","finding":"","journal":"Experimental gerontology","studyType":"Clinical Study"},{"pmid":"30403890","year":"2019","title":"Biometric Alterations of Mouse Embryonic Eye Structures Due to Short-Term Folic Acid Deficiency.","finding":"","journal":"Current eye research","studyType":"Clinical Study"},{"pmid":"28515572","year":"2017","title":"A family of Fe-N-C oxygen reduction electrocatalysts for microbial fuel cell (MFC) application: Relationships between surface chemistry and performances.","finding":"","journal":"Applied catalysis. B, Environmental","studyType":"Clinical Study"},{"pmid":"27346743","year":"2016","title":"Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure.","finding":"","journal":"Progress in neuro-psychopharmacology & biological psychiatry","studyType":"Clinical Study"}],"tags":[{"label":"succinylsulfathiazole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A07AB04","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"kaoxidin","offLabel":[],"synonyms":["succinylsulfathiazole","cremosuxidine","kaoxidin","kaoxidine","succinylsulphathiazole","sulfadigesin","sulfasuccidin","sulfasuccidine","sulfasuccinil","sulfasuccithiazole","sulfasuxidine","sulfenterone"],"timeline":[],"approvals":[],"brandName":"Kaoxidin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"succinylsulfathiazole","explanation":"Think of Kaoxidin like a strong antibiotic that helps stop the growth of bad bacteria in the body. It does this by interfering with the bacteria's ability to make copies of themselves, which ultimately helps to clear up infections. This is similar to how other antibiotics work, but the exact details of Kaoxidin's mechanism are not well understood.","oneSentence":"Kaoxidin works by inhibiting bacterial growth through its antimicrobial properties.","technicalDetail":"Kaoxidin, a succinylsulfathiazole derivative, is thought to exert its antimicrobial effects by inhibiting folic acid synthesis in bacteria, which is essential for their growth and replication."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2490","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=SUCCINYLSULFATHIAZOLE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:42:11.752918","biosimilars":[],"competitors":[],"genericName":"succinylsulfathiazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"002837","UNII":"RSS8647O4S","CHEBI":"CHEBI:9309","INN_ID":"420","RXNORM":"37289","UMLSCUI":"C0075470","ChEMBL_ID":"CHEMBL1484857","KEGG_DRUG":"D07060","DRUGBANK_ID":"DB13580","PUBCHEM_CID":"5315","SNOMEDCT_US":"64669003","MESH_SUPPLEMENTAL_RECORD_UI":"C009342"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"A07AB04","allCodes":["A07AB04"]},"biosimilarFilings":[],"recentPublications":[{"date":"2022 Sep","pmid":"35978220","title":"In-line sample concentration in capillary electrophoresis by cyclodextrin to admicelle microextraction.","journal":"Analytical and bioanalytical chemistry"},{"date":"2021 Jul 15","pmid":"33957263","title":"Succinylsulfathiazole modulates the mTOR signaling pathway in the liver of c57BL/6 mice via a folate independent mechanism.","journal":"Experimental gerontology"},{"date":"2019 Apr","pmid":"30403890","title":"Biometric Alterations of Mouse Embryonic Eye Structures Due to Short-Term Folic Acid Deficiency.","journal":"Current eye research"},{"date":"2017 May 15","pmid":"28515572","title":"A family of Fe-N-C oxygen reduction electrocatalysts for microbial fuel cell (MFC) application: Relationships between surface chemistry and performances.","journal":"Applied catalysis. B, Environmental"},{"date":"2016 Nov 3","pmid":"27346743","title":"Maternal gut and fetal brain connection: Increased anxiety and reduced social interactions in Wistar rat offspring following peri-conceptional antibiotic exposure.","journal":"Progress in neuro-psychopharmacology & biological psychiatry"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Kaoxidin is a small molecule with synonyms including Colistatin, Cremosuxidine, Guanicar, and others. It is classified as a small molecule modality.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}