{"id":"stingless-bee-honey-kelulut","safety":{"commonSideEffects":[{"rate":null,"effect":"Allergic reactions (in individuals with bee product sensitivity)"},{"rate":null,"effect":"Gastrointestinal upset"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Kelulut honey contains high levels of flavonoids, phenolic acids, and other bioactive compounds that scavenge free radicals and inhibit pro-inflammatory cytokine production. These constituents may enhance immune function, promote wound healing, and provide antimicrobial and anti-inflammatory benefits through multiple signaling pathways including NF-κB and MAPK inhibition.","oneSentence":"Stingless bee honey (Kelulut) exerts therapeutic effects through its rich polyphenol and antioxidant content, which reduces oxidative stress and modulates inflammatory pathways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:09:45.862Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Wound healing and tissue repair"},{"name":"Gastrointestinal disorders"},{"name":"Immune system support"},{"name":"Antioxidant and anti-inflammatory conditions"}]},"trialDetails":[{"nctId":"NCT07396441","phase":"PHASE4","title":"Supplementary Kelulut Honey Therapy in Juvenile Open-Angle Glaucoma: Effects on IL-6, RNFL and Dry Eye","status":"RECRUITING","sponsor":"Universiti Sains Malaysia","startDate":"2026-01-15","conditions":"Juvenile Open Angle Glaucoma, Dry Eye Disease (DED), Interleukin 6","enrollment":60},{"nctId":"NCT07279324","phase":"NA","title":"Safety and Efficacy of Kelulut Honey Eyedrops in Dry Eye Disease","status":"NOT_YET_RECRUITING","sponsor":"Universiti Sains Malaysia","startDate":"2026-04-01","conditions":"Dry Eye Disease (DED), Dry Eye Syndrome (DES), Dry Eye Symptoms","enrollment":45},{"nctId":"NCT04849143","phase":"NA","title":"The Effectiveness of Stingless Bee Honey (Kelulut Honey) Versus Gel in Diabetic Wound Bed Preparation","status":"UNKNOWN","sponsor":"Universiti Sains Malaysia","startDate":"2021-09-01","conditions":"Diabetes Mellitus, Wound Heal, Diabetes","enrollment":76},{"nctId":"NCT04438590","phase":"NA","title":"Kelulut Honey as an Alternate Source of Carbo-Loading in Abdominal Surgery Involving the Digestive System","status":"COMPLETED","sponsor":"Universiti Sains Malaysia","startDate":"2020-10-01","conditions":"Insulin Resistance, ERAS","enrollment":64}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":21,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Kelulut"],"phase":"marketed","status":"active","brandName":"Stingless bee honey (Kelulut)","genericName":"Stingless bee honey (Kelulut)","companyName":"Universiti Sains Malaysia","companyId":"universiti-sains-malaysia","modality":"Biologic","firstApprovalDate":"","aiSummary":"Stingless bee honey (Kelulut) exerts therapeutic effects through its rich polyphenol and antioxidant content, which reduces oxidative stress and modulates inflammatory pathways. Used for Wound healing and tissue repair, Gastrointestinal disorders, Immune system support.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}