{"id":"standardized-allergenic-extract-cat-hair","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (erythema, swelling, pruritus)"},{"rate":null,"effect":"Systemic allergic reactions (urticaria, angioedema, bronchospasm)"},{"rate":null,"effect":"Anaphylaxis"}]},"_chembl":{"chemblId":"CHEMBL2108766","moleculeType":"Unknown"},"_dailymed":{"setId":"3c906bb6-6239-038d-e054-00144ff8d46c","title":"STANDARDIZED CAT HAIR ALLERGENIC EXTRACT (FELIS CATUS) SOLUTION [GREER LABORATORIES, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Standardized cat hair allergenic extract is used in allergen immunotherapy (AIT) to gradually desensitize the immune system to cat allergens. By administering increasing doses of the allergen, the therapy promotes a shift from IgE-mediated responses toward IgG-blocking antibodies and regulatory T cell responses, reducing allergic symptoms upon natural exposure to cats.","oneSentence":"This allergenic extract contains cat hair proteins that trigger controlled immune sensitization to desensitize patients to cat allergens through repeated exposure.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:18:24.631Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cat allergy (allergic rhinitis and/or asthma triggered by cat allergen exposure)"}]},"trialDetails":[{"nctId":"NCT06828484","phase":"NA","title":"Allergenic Extract Standardized Cat Hair AP in an Allergic Rhinitis Model.","status":"ACTIVE_NOT_RECRUITING","sponsor":"Queen's University","startDate":"2025-03-04","conditions":"Allergic Rhinitis","enrollment":20},{"nctId":"NCT00595491","phase":"PHASE1","title":"Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation","status":"RECRUITING","sponsor":"Benjamin Medoff","startDate":"2008-01","conditions":"Asthma","enrollment":313},{"nctId":"NCT04035109","phase":"PHASE1, PHASE2","title":"Anakinra as a Rescue Treatment for Allergic Inflammation","status":"WITHDRAWN","sponsor":"University of North Carolina, Chapel Hill","startDate":"2019-12-16","conditions":"Asthma, Allergic","enrollment":""},{"nctId":"NCT01547286","phase":"NA","title":"Imaging Study of the Lungs During an Allergic Asthma Attack","status":"COMPLETED","sponsor":"Massachusetts General Hospital","startDate":"2012-05","conditions":"Asthma, Atopy","enrollment":7},{"nctId":"NCT01612936","phase":"PHASE1","title":"T Cell Effector and Regulatory Mechanisms in Asthma","status":"COMPLETED","sponsor":"Andrew D. Luster, M.D.,Ph.D.","startDate":"2012-09","conditions":"Asthma, Allergies","enrollment":168},{"nctId":"NCT01711593","phase":"PHASE1","title":"Induced Tolerogenic Dendritic Cells as Modulators of Allergic Asthma","status":"COMPLETED","sponsor":"Andrew D. Luster, M.D.,Ph.D.","startDate":"2013-01","conditions":"Asthma, Allergies","enrollment":43},{"nctId":"NCT00689299","phase":"PHASE2","title":"Phase 2 Study in Adults Sensitized to Cat","status":"COMPLETED","sponsor":"Antigen Laboratories, Inc.","startDate":"2008-10","conditions":"Allergy","enrollment":167},{"nctId":"NCT01292070","phase":"EARLY_PHASE1","title":"Safety Evaluation of an Experimental Treatment, Intradermal Human Fcγ1-Fel d1 Fusion Protein (GFD), for Cat Allergy","status":"TERMINATED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2011-03","conditions":"Cat Allergy","enrollment":4}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Standardized Cat Hair Allergenic Extract"],"phase":"marketed","status":"active","brandName":"Standardized Allergenic Extract, Cat Hair","genericName":"Standardized Allergenic Extract, Cat Hair","companyName":"Antigen Laboratories, Inc.","companyId":"antigen-laboratories-inc","modality":"Biologic","firstApprovalDate":"","aiSummary":"This allergenic extract contains cat hair proteins that trigger controlled immune sensitization to desensitize patients to cat allergens through repeated exposure. Used for Cat allergy (allergic rhinitis and/or asthma triggered by cat allergen exposure).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}