{"id":"standard-treatment-in-hiv-positive","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It does this by targeting the viral reverse transcriptase enzyme, preventing the virus from converting its genetic material into DNA that can be integrated into the host cell's genome.","oneSentence":"This drug works by inhibiting the replication of the HIV virus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:36:26.219Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of HIV-1 infection in combination with other antiretroviral agents"}]},"trialDetails":[{"nctId":"NCT04304768","phase":"PHASE4","title":"Opioid, HIV and Immune System","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Miami","startDate":"2020-11-18","conditions":"Immune Defect","enrollment":400},{"nctId":"NCT06593080","phase":"NA","title":"The DECIDE-TB Trial; Validation of Treatment Decision Algorithms for Childhood Tuberculosis","status":"RECRUITING","sponsor":"Chishala Chabala","startDate":"2024-06-01","conditions":"Tuberculosis, Child Health, HIV","enrollment":30240},{"nctId":"NCT05390541","phase":"NA","title":"Increasing HIV/STI Home Testing Via a Digital Intervention Among Black Women","status":"COMPLETED","sponsor":"Johns Hopkins Bloomberg School of Public Health","startDate":"2022-02-02","conditions":"Hiv, Sexually Transmitted Diseases, Economic Problems","enrollment":3},{"nctId":"NCT07125235","phase":"NA","title":"Reactive Driven Support for Treatment, Adherence, Resilience, and Thriving (reSTART) Clinical Trial","status":"RECRUITING","sponsor":"University of California, San Francisco","startDate":"2026-02-09","conditions":"Behavioral Intervention, Viral Suppression of HIV Infection, ART Adherence","enrollment":270},{"nctId":"NCT03133728","phase":"","title":"Diagnosis of HIV and Early Antiretroviral Therapy Initiation Among HIV-1 Infected Infants","status":"COMPLETED","sponsor":"University of Alabama at Birmingham","startDate":"2019-05-30","conditions":"HIV Infections, Hiv","enrollment":1682},{"nctId":"NCT06857071","phase":"NA","title":"Expanded Social Network Recruitment to HIV Testing (E-SNRHT) Intervention to Locate Undiagnosed Cases and Reduce HIV-related Stigma","status":"RECRUITING","sponsor":"University of Illinois at Chicago","startDate":"2025-09-30","conditions":"Undiagnosed HIV Infection, Populations That Are Reluctant to Test for HIV, Long-term Undiagnosed HIV Infection","enrollment":2480},{"nctId":"NCT03848858","phase":"NA","title":"Efficacy of EMDR Therapy, as Compared to Treatment as Usual, in Reducing Clinical Symptoms in People With HIV","status":"COMPLETED","sponsor":"Parc de Salut Mar","startDate":"2019-02-01","conditions":"HIV/AIDS, Psychological Trauma, PTSD","enrollment":40},{"nctId":"NCT07209917","phase":"NA","title":"Secondary Cervical Cancer Prevention of Vulnerable Women With HPV and HIV Co-infection in India","status":"RECRUITING","sponsor":"University of California, Irvine","startDate":"2026-02-01","conditions":"Cervical Cancer, Human Papillomavirus (HPV) Infection, Human Immunodeficiency Virus (HIV) Infection","enrollment":420},{"nctId":"NCT07419568","phase":"NA","title":"Burden of Tuberculosis Among Pregnant and Postpartum Women in Guinea-Bissau","status":"NOT_YET_RECRUITING","sponsor":"Aarhus University Hospital","startDate":"2026-02","conditions":"Tuberculosis (TB), Tuberculosis Infection, Latent, Pregnancy","enrollment":720},{"nctId":"NCT07406490","phase":"","title":"Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System","status":"NOT_YET_RECRUITING","sponsor":"University of Florida","startDate":"2026-07-01","conditions":"Hepatitis C Virus (HCV), Hepatitis C Virus (HCV) Infection, HIV (Human Immunodeficiency Virus)","enrollment":6466},{"nctId":"NCT06886971","phase":"NA","title":"Strategies to AchieVe Viral Suppression for Youth With HIV","status":"RECRUITING","sponsor":"Johns Hopkins University","startDate":"2024-11-10","conditions":"Human Immunodeficiency Virus (HIV) Infection","enrollment":288},{"nctId":"NCT04298905","phase":"NA","title":"Leveraging mHealth to Enable and Adapt CHW Strategies to Improve TB/HIV Patient Outcomes in SA","status":"ACTIVE_NOT_RECRUITING","sponsor":"Johns Hopkins University","startDate":"2022-03-10","conditions":"Adherence, Patient, TB, HIV/AIDS","enrollment":62},{"nctId":"NCT06971367","phase":"NA","title":"IBIS Megastudy of Interventions to Encourage HIV Retesting","status":"RECRUITING","sponsor":"University of California, San Francisco","startDate":"2025-12-09","conditions":"HIV","enrollment":40000},{"nctId":"NCT06814041","phase":"NA","title":"Pilot RCT and Interview Study on an HIV Chatbot in Nigeria","status":"ACTIVE_NOT_RECRUITING","sponsor":"Christoph Pimmer","startDate":"2025-04-14","conditions":"HIV","enrollment":314},{"nctId":"NCT06708351","phase":"NA","title":"Enhancing Cervical Cancer Screening and Treatment in Women Living With HIV in Kenya, the ENHANCE LINKAge Trial","status":"NOT_YET_RECRUITING","sponsor":"Emory University","startDate":"2026-03-31","conditions":"HIV Infection, Human Papillomavirus-Related Cervical Carcinoma, Screening Strategy","enrollment":2280},{"nctId":"NCT03831906","phase":"NA","title":"Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia)","status":"COMPLETED","sponsor":"Institut National de la Santé Et de la Recherche Médicale, France","startDate":"2019-03-20","conditions":"Tuberculosis, Severe Pneumonia, Covid19","enrollment":2570},{"nctId":"NCT06501781","phase":"NA","title":"Peer Behavioral Activation Utilization to Improve Substance Use and HIV Outcomes in People Receiving Long Acting Injectable-PrEP/ART (PUSH)","status":"RECRUITING","sponsor":"University of Maryland, Baltimore","startDate":"2025-03-18","conditions":"HIV Infections, Substance Use","enrollment":186},{"nctId":"NCT05358795","phase":"NA","title":"Family Connections Cluster RCT in Zambia","status":"COMPLETED","sponsor":"Johns Hopkins Bloomberg School of Public Health","startDate":"2023-04-01","conditions":"HIV, Adolescent Development, Adolescent Behavior","enrollment":1386},{"nctId":"NCT06762730","phase":"PHASE4","title":"Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals","status":"RECRUITING","sponsor":"Hadassah Medical Organization","startDate":"2024-12-09","conditions":"HIV Infected Individuals, Osteopenia","enrollment":110},{"nctId":"NCT06743204","phase":"NA","title":"The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study","status":"RECRUITING","sponsor":"Johns Hopkins University","startDate":"2025-09-08","conditions":"Gonorrhea Female, Chlamydia Females, Syphilis Female","enrollment":5560},{"nctId":"NCT07167069","phase":"","title":"India HIV-CervCa Project","status":"ACTIVE_NOT_RECRUITING","sponsor":"Abramson Cancer Center at Penn Medicine","startDate":"2021-02-09","conditions":"HIV Positive, HIV Negative, Cervical Cancer","enrollment":180},{"nctId":"NCT06737380","phase":"PHASE1","title":"UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients","status":"RECRUITING","sponsor":"LiveKidney.Bio","startDate":"2025-01-07","conditions":"SLE, Lupus, Systemic Lupus Erthematosus","enrollment":10},{"nctId":"NCT06585631","phase":"NA","title":"The Collaborative Care PrTNER Study","status":"RECRUITING","sponsor":"Children's Hospital of Philadelphia","startDate":"2025-01-02","conditions":"HIV, Substance Use Disorders, Substance Use","enrollment":275},{"nctId":"NCT04725617","phase":"NA","title":"Wellness Intervention for Smoking and HIV","status":"RECRUITING","sponsor":"University of Arizona","startDate":"2021-11-16","conditions":"HIV, Sleep, Smoking Cessation","enrollment":200},{"nctId":"NCT07112001","phase":"NA","title":"A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression","status":"RECRUITING","sponsor":"University of Florida","startDate":"2025-07-31","conditions":"HIV, Depression, Anxiety","enrollment":60},{"nctId":"NCT06751030","phase":"","title":"Community, Home-based Education, Screening Services Strategy to Increase Cervical Cancer Control Access for HIV-Positive Women in Nigeria","status":"RECRUITING","sponsor":"Emory University","startDate":"2024-12-03","conditions":"HIV, Cervical Cancer","enrollment":1500},{"nctId":"NCT07103928","phase":"NA","title":"Prison-Based HIV Partner Notification","status":"NOT_YET_RECRUITING","sponsor":"University of Illinois at Chicago","startDate":"2026-01","conditions":"HIV","enrollment":216},{"nctId":"NCT04446611","phase":"NA","title":"Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)","status":"COMPLETED","sponsor":"Foundation for Professional Development (Pty) Ltd","startDate":"2021-03-29","conditions":"Sexually Transmitted Infection, HIV/AIDS, Cost-effectiveness","enrollment":2247},{"nctId":"NCT06890988","phase":"NA","title":"Ending the Epidemic Interventions in the Dental Setting - UH3","status":"RECRUITING","sponsor":"Columbia University","startDate":"2025-03-31","conditions":"HIV-1-infection","enrollment":128},{"nctId":"NCT06515301","phase":"NA","title":"Key Interventions to Improve the Follow-up Adherence Post Cervical Precancerous Lesion Treatment in Ethiopia","status":"RECRUITING","sponsor":"Addis Ababa University","startDate":"2024-11-20","conditions":"Suspicious Cervical Cancer Lesions Follow up Adherence","enrollment":466},{"nctId":"NCT04487041","phase":"PHASE4","title":"Tfh Dysfunction in HIV and Aging","status":"RECRUITING","sponsor":"University of Miami","startDate":"2020-10-30","conditions":"Human Influenza","enrollment":400},{"nctId":"NCT04772469","phase":"NA","title":"Self-Test Strategies and Linkage Incentives to Improve ART and PrEP Uptake in Men","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2021-03-22","conditions":"Human Immunodeficiency Virus, Acquired Immunodeficiency Syndrome, HIV Infections","enrollment":934},{"nctId":"NCT04026867","phase":"NA","title":"The DETECT HCV Linkage to Care Trial","status":"COMPLETED","sponsor":"Denver Health and Hospital Authority","startDate":"2019-11-20","conditions":"Hepatitis C","enrollment":309},{"nctId":"NCT02797470","phase":"PHASE1, PHASE2","title":"Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant","status":"ACTIVE_NOT_RECRUITING","sponsor":"AIDS Malignancy Consortium","startDate":"2016-06-23","conditions":"HIV Infection, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Plasmablastic Lymphoma","enrollment":11},{"nctId":"NCT06919679","phase":"PHASE2","title":"Phase II Trial of BrECADD in HIV-Positive Patients With Advanced-Stage Classical Hodgkin Lymphoma","status":"NOT_YET_RECRUITING","sponsor":"University of Cologne","startDate":"2025-08","conditions":"Hodgkin Lymphoma (Category)","enrollment":35},{"nctId":"NCT04994444","phase":"PHASE2, PHASE3","title":"Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts","status":"COMPLETED","sponsor":"Brown University","startDate":"2021-09-01","conditions":"Tobacco Use Cessation","enrollment":49},{"nctId":"NCT05452616","phase":"NA","title":"Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of Tuberculosis","status":"COMPLETED","sponsor":"University Hospital, Basel, Switzerland","startDate":"2022-10-19","conditions":"Human Immunodeficiency Virus (HIV) Infection","enrollment":610},{"nctId":"NCT06907056","phase":"PHASE4","title":"Effectiveness and Safety of Darunavir/Cobicistat Plus Lamivudine Versus Darunavir/Cobicistat Plus Tenofovir/Emtricitabine in Virologically Suppressed HIV-1-positive Individuals in Mexico","status":"RECRUITING","sponsor":"José Antonio Mata Marín","startDate":"2023-11-09","conditions":"HIV Infection","enrollment":138},{"nctId":"NCT01152918","phase":"NA","title":"Evaluating Methods to Increase HIV Testing, Access to HIV Care, and HIV Prevention Strategies","status":"COMPLETED","sponsor":"HIV Prevention Trials Network","startDate":"2010-09","conditions":"HIV Infection","enrollment":18442},{"nctId":"NCT03484533","phase":"NA","title":"HIV Self Testing of Male Partners of Women in PMTCT","status":"COMPLETED","sponsor":"University of Washington","startDate":"2018-05-17","conditions":"ART Adherence, PMTCT, Linkage to Care","enrollment":736},{"nctId":"NCT06880224","phase":"NA","title":"Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study","status":"RECRUITING","sponsor":"Northwestern University","startDate":"2025-02-01","conditions":"Adolescent HIV Infection","enrollment":500},{"nctId":"NCT04973254","phase":"NA","title":"Improving Treatment and Retention Adherence in Nontraditional Settings","status":"COMPLETED","sponsor":"Boston Medical Center","startDate":"2022-02-23","conditions":"HIV Infections","enrollment":25},{"nctId":"NCT02677025","phase":"NA","title":"Young Women's Health CoOp (Cooperative) in Cape Town","status":"COMPLETED","sponsor":"RTI International","startDate":"2014-05","conditions":"HIV, Substance Abuse","enrollment":100},{"nctId":"NCT02928900","phase":"NA","title":"Patient Actor Training to Improve HIV Services for Adolescents in Kenya","status":"COMPLETED","sponsor":"University of Washington","startDate":"2016-09-26","conditions":"HIV/AIDS","enrollment":24},{"nctId":"NCT04383769","phase":"","title":"Differentiated Service Delivery for Antiretroviral Therapy","status":"COMPLETED","sponsor":"Thai Red Cross AIDS Research Centre","startDate":"2019-12-15","conditions":"HIV Infections","enrollment":5000},{"nctId":"NCT03203265","phase":"NA","title":"Innovative Strategy to Offer Online Test and Treat for Thai MSM/TG","status":"COMPLETED","sponsor":"Thai Red Cross AIDS Research Centre","startDate":"2015-04-06","conditions":"HIV/AIDS","enrollment":600},{"nctId":"NCT05602376","phase":"NA","title":"Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging","status":"RECRUITING","sponsor":"Desmond Tutu HIV Foundation","startDate":"2023-03-31","conditions":"HIV Infections, Men, Treatment Adherence","enrollment":3642},{"nctId":"NCT04930367","phase":"NA","title":"CombinADO: Evaluation of an Intervention Aimed At Improving HIV Outcomes Among Adolescents and Young Adults Living with HIV in Mozambique","status":"COMPLETED","sponsor":"Columbia University","startDate":"2021-09-13","conditions":"HIV","enrollment":1715},{"nctId":"NCT04032522","phase":"","title":"Neonatal HIV Early Infant Diagnosis (EID) Versus Standard of Care EID- Long Term Impact on inFant hEalth (LIFE)","status":"COMPLETED","sponsor":"Michael Hoelscher","startDate":"2019-10-23","conditions":"HIV, Neonatal HIV Early-Infant-Diagnosis (EID), Point-of-Care Testing (PoC)","enrollment":6602},{"nctId":"NCT03092531","phase":"NA","title":"Positive Steps to Enhance Problem Solving Skills","status":"COMPLETED","sponsor":"University of California, Los Angeles","startDate":"2018-02-01","conditions":"Adherence","enrollment":123},{"nctId":"NCT04121195","phase":"PHASE2, PHASE3","title":"Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load","status":"COMPLETED","sponsor":"University of Liverpool","startDate":"2020-10-30","conditions":"HIV/AIDS, Tuberculosis","enrollment":26},{"nctId":"NCT06326294","phase":"NA","title":"Assessment of the Effectiveness of TA Versus LEEP for Cervical Cancer Risk Reduction in WLHIV in Mozambique","status":"RECRUITING","sponsor":"Instituto Nacional de Saúde, Mozambique","startDate":"2024-04-17","conditions":"HIV Infections, HPV Infection, CIN 2/3","enrollment":4844},{"nctId":"NCT04364165","phase":"NA","title":"Effect of U=U Messaging on HIV in South Africa","status":"COMPLETED","sponsor":"University of Pennsylvania","startDate":"2020-03-02","conditions":"HIV/AIDS","enrollment":1048},{"nctId":"NCT05405582","phase":"NA","title":"Thetha Nami Ngithethe Nawe (\"Let's Talk\"): Step Wedge cRCT of Peer Led Community PrEP and SRH for Youth in South Africa","status":"UNKNOWN","sponsor":"Africa Health Research Institute","startDate":"2022-05-26","conditions":"HIV-1-infection, Sexually Transmitted Diseases","enrollment":6000},{"nctId":"NCT04532307","phase":"NA","title":"Isisekelo Sempilo Trial to Optimize Peer (Thetha Nami) Delivery of HIV Prevention to Young People in Rural KwaZulu-Natal","status":"COMPLETED","sponsor":"Africa Health Research Institute","startDate":"2020-03-12","conditions":"HIV Prevention","enrollment":1743},{"nctId":"NCT03809364","phase":"NA","title":"Pilot Test of a Couple-Based Medication Adherence Intervention for HIV-Positive Women and Their Male Partners in South Africa","status":"COMPLETED","sponsor":"University of Maryland, College Park","startDate":"2021-11-01","conditions":"Human Immunodeficiency Virus","enrollment":40},{"nctId":"NCT03930992","phase":"PHASE3","title":"Efficacy of Zoledronic Acid + Colaren vs Zoledronic Acid + Conventional Treatment for Osteoporosis in HIV+ and HIV- Men","status":"COMPLETED","sponsor":"University of Guadalajara","startDate":"2019-04-17","conditions":"Secondary Osteoporosis","enrollment":30},{"nctId":"NCT03762187","phase":"NA","title":"A Brief Affirmation Intervention on HIV-related Distress and Positive Living in Lesotho","status":"COMPLETED","sponsor":"University of California, Santa Barbara","startDate":"2014-09-01","conditions":"Self-affirmation Plus Positive Living Counseling, Counseling","enrollment":389},{"nctId":"NCT03624413","phase":"NA","title":"InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media","status":"COMPLETED","sponsor":"Emory University","startDate":"2021-04-15","conditions":"HIV-1-infection, Adolescent Behavior","enrollment":80},{"nctId":"NCT01532609","phase":"NA","title":"Methadone Maintenance and HIV Prevention: A Window of Opportunity in China","status":"COMPLETED","sponsor":"University of California, Los Angeles","startDate":"2009-03","conditions":"Capacity Building, Drug Use, HIV/AIDS","enrollment":220},{"nctId":"NCT06058286","phase":"NA","title":"MENJAGA: Continuous Quality Improvement for Antenatal HIV, Syphilis and Hepatitis B Testing in Indonesia","status":"UNKNOWN","sponsor":"Yanri Wijayanti Subronto, MD, PhD,","startDate":"2023-10-01","conditions":"Hiv, Syphilis, Hepatitis B","enrollment":2000},{"nctId":"NCT06044792","phase":"","title":"The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in PLWH","status":"NOT_YET_RECRUITING","sponsor":"Medical University of Warsaw","startDate":"2023-09-30","conditions":"Hiv, AIDS, CD4 Deficiency","enrollment":50},{"nctId":"NCT03149237","phase":"NA","title":"Partners-based HIV Treatment for Couples Attending Antenatal Care","status":"COMPLETED","sponsor":"Vanderbilt University Medical Center","startDate":"2017-11-16","conditions":"Human Immunodeficiency Virus","enrollment":2160},{"nctId":"NCT02848235","phase":"NA","title":"Kenya Enhanced Mentor Mother ProgrAm (EMMA)","status":"COMPLETED","sponsor":"Henry M. Jackson Foundation for the Advancement of Military Medicine","startDate":"2017-01-18","conditions":"HIV, Pregnancy","enrollment":363},{"nctId":"NCT03555669","phase":"NA","title":"Project SOAR-Mental Health Malawi: Depression and HIV Integration","status":"COMPLETED","sponsor":"University of North Carolina, Chapel Hill","startDate":"2017-04-24","conditions":"Depression, HIV/AIDS","enrollment":2082},{"nctId":"NCT03704805","phase":"NA","title":"Effect of a Psychological Intervention on Antiretroviral Therapy and Mental Health Outcomes in HIV-positive Adults in Zimbabwe","status":"COMPLETED","sponsor":"University of Bern","startDate":"2018-10-05","conditions":"Mental Disorder, HIV Infections","enrollment":480},{"nctId":"NCT03290391","phase":"PHASE4","title":"Linking Infectious and Narcology Care-Part II","status":"COMPLETED","sponsor":"Boston Medical Center","startDate":"2018-09-19","conditions":"HIV Infection, Drug Use","enrollment":225},{"nctId":"NCT03194477","phase":"NA","title":"Providing Unique Support for Health (PUSH) Study","status":"COMPLETED","sponsor":"Johns Hopkins Bloomberg School of Public Health","startDate":"2017-08-01","conditions":"HIV-1-infection","enrollment":631},{"nctId":"NCT04330989","phase":"NA","title":"An Integrated Strategy to Support Antiretroviral Therapy and Pre-exposure Prophylaxis Adherence for HIV Prevention in Pregnant and Breastfeeding Women","status":"COMPLETED","sponsor":"University of North Carolina, Chapel Hill","startDate":"2020-03-01","conditions":"HIV-1-infection, Antenatal Care","enrollment":300},{"nctId":"NCT04514848","phase":"NA","title":"Point of Care Tests for Syphilis and HIV","status":"COMPLETED","sponsor":"University of Alberta","startDate":"2020-07-27","conditions":"Syphilis","enrollment":1526},{"nctId":"NCT05636254","phase":"","title":"Diagnostic Accuracy of Imaging Findings in TBM/Spinal Tubercular Arachnoiditis and Correlation With Outcomes","status":"UNKNOWN","sponsor":"All India Institute of Medical Sciences","startDate":"2022-01-27","conditions":"Tuberculous Meningitis, Tuberculous Arachnoiditis","enrollment":120},{"nctId":"NCT03489109","phase":"NA","title":"2-5 Intermittent Caloric Restriction in HIV","status":"TERMINATED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2018-05-09","conditions":"Human Immunodeficiency Virus, Metabolic Syndrome","enrollment":35},{"nctId":"NCT00822120","phase":"PHASE2","title":"S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma","status":"COMPLETED","sponsor":"SWOG Cancer Research Network","startDate":"2009-07","conditions":"Lymphoma, Nonneoplastic Condition","enrollment":371},{"nctId":"NCT03834571","phase":"PHASE2","title":"Testing the Addition of Paclitaxel and Carboplatin Given After Standard Chemotherapy and Radiation for Cervical Cancer in HIV-positive Women","status":"WITHDRAWN","sponsor":"AIDS Malignancy Consortium","startDate":"2022-05-31","conditions":"Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified","enrollment":""},{"nctId":"NCT02796027","phase":"NA","title":"BRIDGE: Improving HIV Service Delivery for People Who Inject Drugs","status":"COMPLETED","sponsor":"Columbia University","startDate":"2017-02-01","conditions":"Human Immunodeficiency Virus, Substance Abuse, Intravenous","enrollment":616},{"nctId":"NCT01926184","phase":"NA","title":"RCT of an Integrative Intervention for Non-Treatment-Seeking Meth Users","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2013-01","conditions":"HIV/AIDS, Stimulant Use Disorders","enrollment":110},{"nctId":"NCT03600142","phase":"NA","title":"A Stigma Reduction Intervention at Time of Entry Into Antenatal Care to Improve PMTCT Services in Tanzania","status":"COMPLETED","sponsor":"University of Utah","startDate":"2019-04-08","conditions":"HIV Infections","enrollment":1539},{"nctId":"NCT04327921","phase":"NA","title":"A Peer Navigator Model to Improve Quit Attempts and Smoking Cessation Rates Among HIV-positive Smokers","status":"COMPLETED","sponsor":"Brown University","startDate":"2020-01-14","conditions":"HIV","enrollment":66},{"nctId":"NCT03098693","phase":"","title":"Dyadic-Based Diagnosis, Care, and Prevention for HIV Discordant Couples in Tanzania","status":"COMPLETED","sponsor":"Medical University of South Carolina","startDate":"2017-11-21","conditions":"HIV","enrollment":128},{"nctId":"NCT02583048","phase":"PHASE2","title":"Evaluating the Safety, Tolerability, and Pharmacokinetics of Bedaquiline and Delamanid, Alone and in Combination, For Drug-Resistant Pulmonary Tuberculosis","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2016-08-15","conditions":"Tuberculosis, HIV Infections","enrollment":84},{"nctId":"NCT00344487","phase":"NA","title":"Pilot Study of Effect of Kaletra on CD4 Response in HIV Positive (+) Patients With Viral Suppression KIMBO Study","status":"TERMINATED","sponsor":"University of Maryland, Baltimore","startDate":"2005-12","conditions":"HIV","enrollment":3},{"nctId":"NCT03099707","phase":"NA","title":"The Treatment Ambassador Program: A Pilot Intervention to Increase Treatment Initiation","status":"COMPLETED","sponsor":"Brigham and Women's Hospital","startDate":"2017-04-12","conditions":"HIV","enrollment":84},{"nctId":"NCT04035759","phase":"PHASE1","title":"Positive Affect Promotion to Empower Optimal Adherence to HIV Therapy","status":"COMPLETED","sponsor":"State University of New York - Downstate Medical Center","startDate":"2019-10-16","conditions":"HIV/AIDS","enrollment":20},{"nctId":"NCT01904994","phase":"NA","title":"Link4Health: A Combination Strategy for Linkage and Retention, Swaziland","status":"COMPLETED","sponsor":"Columbia University","startDate":"2013-08","conditions":"HIV (Human Immunodeficiency Virus)","enrollment":2201},{"nctId":"NCT04191278","phase":"PHASE4","title":"Mobile Health Interventions for Medication Adherence Among PLWH","status":"WITHDRAWN","sponsor":"Duke University","startDate":"2021-11","conditions":"HIV/AIDS, Smoking, Smoking Cessation","enrollment":""},{"nctId":"NCT04021953","phase":"NA","title":"The People Like Us Evaluation Study","status":"COMPLETED","sponsor":"National University of Singapore","startDate":"2019-10-13","conditions":"HIV/AIDS, Sexually Transmitted Infection, Homosexuality","enrollment":300},{"nctId":"NCT00017810","phase":"PHASE2","title":"The Healthy Life Choices Project in HIV-Positive Patients","status":"COMPLETED","sponsor":"Columbia University","startDate":"1996-09","conditions":"Diarrhea, HIV Infections","enrollment":75},{"nctId":"NCT04359095","phase":"PHASE2, PHASE3","title":"Effectiveness and Safety of Medical Treatment for SARS-CoV-2 (COVID-19) in Colombia","status":"COMPLETED","sponsor":"Universidad Nacional de Colombia","startDate":"2020-08-18","conditions":"COVID-19","enrollment":650},{"nctId":"NCT02338024","phase":"NA","title":"Enhancing Linkage to HIV Care for Newly Detected HIV-positive Persons in Ukraine","status":"COMPLETED","sponsor":"Ukrainian Institute on Public Health Policy","startDate":"2015-10-22","conditions":"HIV","enrollment":276},{"nctId":"NCT03630549","phase":"PHASE4","title":"Village-based vs Clinic-based ART Care - a Cluster Randomized Controlled Trial in Lesotho","status":"COMPLETED","sponsor":"Niklaus Labhardt","startDate":"2018-08-16","conditions":"HIV/AIDS","enrollment":257},{"nctId":"NCT03739736","phase":"","title":"TB Reduction Through ART and TB Screening Project","status":"UNKNOWN","sponsor":"London School of Hygiene and Tropical Medicine","startDate":"2018-06-12","conditions":"Tuberculosis, HIV/AIDS","enrollment":4200},{"nctId":"NCT02693145","phase":"NA","title":"Cooperative Re-Engagement Controlled Trial (CoRECT)","status":"COMPLETED","sponsor":"Centers for Disease Control and Prevention","startDate":"2016-08","conditions":"Human Immunodeficiency Virus","enrollment":1893},{"nctId":"NCT02562092","phase":"NA","title":"The Georgia Latino AIDS/HIV Diagnosis and Linkage in Youth (GLADLY) Project","status":"TERMINATED","sponsor":"Emory University","startDate":"2015-08","conditions":"HIV","enrollment":2},{"nctId":"NCT03454373","phase":"NA","title":"Long Term Follow-Up of Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania","status":"COMPLETED","sponsor":"University of California, Berkeley","startDate":"2018-03-01","conditions":"Hiv","enrollment":800},{"nctId":"NCT03163277","phase":"PHASE4","title":"Using Less Neurotoxic Drugs in Patients With HAND (MARAND-X)","status":"TERMINATED","sponsor":"Giovanni Di Perri","startDate":"2017-05-15","conditions":"Hiv, Neurocognitive Dysfunction","enrollment":38},{"nctId":"NCT03931083","phase":"","title":"Screening Test Accuracy of Gynocular™, HR-HPV Testing, VIA for Detection of Cervical Neoplastic Lesions, in Women Living With HIV","status":"UNKNOWN","sponsor":"University of Bern","startDate":"2019-05-08","conditions":"Uterine Cervical Neoplasms, HIV/AIDS","enrollment":450},{"nctId":"NCT04598958","phase":"NA","title":"A Multidisciplinary \"Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)\" Intervention to Improve Maternal and Child Outcomes in Lesotho","status":"COMPLETED","sponsor":"Elizabeth Glaser Pediatric AIDS Foundation","startDate":"2016-07-27","conditions":"Human Immunodeficiency Virus","enrollment":1004},{"nctId":"NCT02238327","phase":"","title":"Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes","status":"COMPLETED","sponsor":"University of Pittsburgh","startDate":"2014-09","conditions":"Chronic Obstructive Pulmonary Disease, HIV, Emphysema","enrollment":232},{"nctId":"NCT03723525","phase":"PHASE4","title":"Package of Care to Improve Retention in ART and Mortality Among Treatment Naive HIV Infected Individuals","status":"COMPLETED","sponsor":"National Centre for AIDs and STD Control, Nepal","startDate":"2018-01-22","conditions":"HIV","enrollment":1073},{"nctId":"NCT03478137","phase":"NA","title":"Obstructive Sleep Apnea, CPAP Treatment & Cognitive Ability in HIV","status":"UNKNOWN","sponsor":"McGill University","startDate":"2017-06-05","conditions":"Hiv, Obstructive Sleep Apnea, Cognitive Change","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["plus Zoledronic Acid 4 mg"],"phase":"phase_3","status":"active","brandName":"standard treatment in HIV positive","genericName":"standard treatment in HIV positive","companyName":"University of Guadalajara","companyId":"university-of-guadalajara","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This drug works by inhibiting the replication of the HIV virus. Used for Treatment of HIV-1 infection in combination with other antiretroviral agents.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}