{"id":"stamaril","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Headache"},{"rate":"10-30","effect":"Myalgia"},{"rate":"5-15","effect":"Fever"},{"rate":"5-10","effect":"Injection site reaction"},{"rate":"5-15","effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL2108816","moleculeType":"Vaccine component"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains a weakened strain of yellow fever virus (17D strain) that replicates in the body without causing disease, triggering both humoral (antibody) and cell-mediated immune responses. This provides long-term protection against infection with wild-type yellow fever virus. The vaccine has been in use for decades and is considered one of the most effective vaccines available.","oneSentence":"Stamaril is a live attenuated yellow fever vaccine that stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:36:03.599Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Yellow fever prevention in endemic regions and travelers to yellow fever-endemic areas"}]},"trialDetails":[{"nctId":"NCT01262872","phase":"PHASE2","title":"Impact of GSK Biologicals' 2189242A Vaccine on Nasopharyngeal Carriage, Safety & Immunogenicity in Children & Infants","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2011-02-09","conditions":"Infections, Streptococcal","enrollment":1320},{"nctId":"NCT00436007","phase":"PHASE2","title":"Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-04-30","conditions":"Malaria","enrollment":511},{"nctId":"NCT00982137","phase":"PHASE2","title":"Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®)","status":"COMPLETED","sponsor":"Sanofi","startDate":"2004-07","conditions":"Japanese Encephalitis, Yellow Fever","enrollment":108}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":29,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Yellow Fever Vaccine","Yellow Fever (YF) Vaccine","YF17D vaccine"],"phase":"phase_3","status":"active","brandName":"Stamaril™","genericName":"Stamaril™","companyName":"GlaxoSmithKline","companyId":"glaxosmithkline","modality":"Biologic","firstApprovalDate":"","aiSummary":"Stamaril is a live attenuated yellow fever vaccine that stimulates the immune system to produce antibodies and cellular immunity against yellow fever virus. Used for Yellow fever prevention in endemic regions and travelers to yellow fever-endemic areas.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}