{"id":"staloral-tm","safety":{"commonSideEffects":[{"rate":null,"effect":"Oral pruritus"},{"rate":null,"effect":"Throat irritation"},{"rate":null,"effect":"Edema of mouth or throat"},{"rate":null,"effect":"Gastrointestinal symptoms"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Staloral works by gradually exposing the patient to increasing doses of allergen extract under the tongue, which promotes immune tolerance and reduces allergic responses. This sublingual immunotherapy approach shifts the immune response from Th2-mediated (allergic) to Th1-mediated (tolerant) pathways, thereby reducing symptoms upon natural allergen exposure.","oneSentence":"Staloral is an allergen immunotherapy tablet that desensitizes the immune system to specific allergens through sublingual administration.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:09:03.867Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis and/or allergic asthma caused by grass pollen allergens"}]},"trialDetails":[{"nctId":"NCT00172341","phase":"PHASE4","title":"Sublingual Immunotherapy With House Dust Mite Extract in Asthmatic Children","status":"UNKNOWN","sponsor":"National Taiwan University Hospital","startDate":"","conditions":"Asthma","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Staloral TM","genericName":"Staloral TM","companyName":"National Taiwan University Hospital","companyId":"national-taiwan-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Staloral is an allergen immunotherapy tablet that desensitizes the immune system to specific allergens through sublingual administration. Used for Allergic rhinitis and/or allergic asthma caused by grass pollen allergens.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}