{"id":"ssr591813l-dianicline","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL187927","moleculeType":"Small molecule","molecularWeight":"216.28"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Dianicline works by selectively inhibiting the norepinephrine transporter, increasing the concentration of norepinephrine in the synaptic cleft, which enhances the activity of norepinephrine in the brain. This is thought to improve cognitive function and potentially treat conditions such as attention deficit hyperactivity disorder (ADHD).","oneSentence":"SSR591813L (dianicline) is a norepinephrine reuptake inhibitor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:53:20.979Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of attention deficit hyperactivity disorder (ADHD)"}]},"trialDetails":[{"nctId":"NCT00387946","phase":"PHASE3","title":"Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)","status":"COMPLETED","sponsor":"Sanofi","startDate":"2006-09","conditions":"Smoking Cessation, Tobacco Use Cessation","enrollment":630}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"SSR591813L (dianicline)","genericName":"SSR591813L (dianicline)","companyName":"Sanofi","companyId":"sanofi","modality":"Small molecule","firstApprovalDate":"","aiSummary":"SSR591813L (dianicline) is a norepinephrine reuptake inhibitor. Used for Treatment of attention deficit hyperactivity disorder (ADHD).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}