{"id":"sputnik-light","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or swelling"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Myalgia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Sputnik Light uses a recombinant adenovirus type 5 (Ad5) as a viral vector to introduce genetic material encoding the SARS-CoV-2 spike protein into host cells. This triggers both cellular and humoral immune responses, generating T-cell and antibody-mediated immunity against the virus. It is administered as a single-dose vaccine or as a booster component in heterologous prime-boost regimens.","oneSentence":"Sputnik Light is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate adaptive immune responses against COVID-19.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:36:00.215Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"COVID-19 prevention (SARS-CoV-2 infection)"}]},"trialDetails":[{"nctId":"NCT06057025","phase":"PHASE3","title":"Study of \"Sputnik Lite\" for the Prevention of COVID-19 With Altered Antigenic Composition.","status":"UNKNOWN","sponsor":"Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation","startDate":"2023-09","conditions":"COVID-19","enrollment":50},{"nctId":"NCT04741061","phase":"PHASE3","title":"Study to Evaluate Efficacy, Immunogenicity and Safety of the Sputnik-Light","status":"UNKNOWN","sponsor":"Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation","startDate":"2021-02-19","conditions":"COVID-19 Prevention","enrollment":6000},{"nctId":"NCT04713488","phase":"PHASE1, PHASE2","title":"An Open Study on the Safety, Tolerability, and Immunogenicity of \"Sputnik Light\" Vaccine","status":"UNKNOWN","sponsor":"Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation","startDate":"2021-01-15","conditions":"COVID-19 Prevention","enrollment":110}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":17,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["vector vaccine to help prevent the SARS-CoV-2-induced coronavirus infection"],"phase":"phase_3","status":"active","brandName":"Sputnik Light","genericName":"Sputnik Light","companyName":"Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation","companyId":"gamaleya-research-institute-of-epidemiology-and-microbiology-health-ministry-of","modality":"Biologic","firstApprovalDate":"","aiSummary":"Sputnik Light is a viral vector vaccine that delivers the SARS-CoV-2 spike protein gene to stimulate adaptive immune responses against COVID-19. Used for COVID-19 prevention (SARS-CoV-2 infection).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}