{"id":"spherule-derived-coccidioidin","safety":{"commonSideEffects":[{"rate":"null","effect":"Local reaction at injection site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The vaccine works by introducing antigens from the Coccidioides fungus to the body, which triggers an immune response and helps the body to recognize and fight the fungus. This is particularly useful for individuals who are at high risk of contracting coccidioidomycosis, a fungal infection caused by the Coccidioides fungus.","oneSentence":"Spherule-derived coccidioidin is a vaccine derived from the spherules of the Coccidioides fungus, which stimulates an immune response against the fungus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:35:52.441Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Coccidioidomycosis prevention in individuals at high risk"}]},"trialDetails":[{"nctId":"NCT00690092","phase":"PHASE3","title":"A Multi-center Study of Spherule-Derived Coccidioidin","status":"COMPLETED","sponsor":"Nielsen BioSciences, Inc.","startDate":"2005-05","conditions":"Coccidioidomycosis","enrollment":113}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Coccidioidin SD (proposed trade name)"],"phase":"phase_3","status":"active","brandName":"Spherule-derived coccidioidin","genericName":"Spherule-derived coccidioidin","companyName":"Nielsen BioSciences, Inc.","companyId":"nielsen-biosciences-inc","modality":"Biologic","firstApprovalDate":"","aiSummary":"Spherule-derived coccidioidin is a vaccine derived from the spherules of the Coccidioides fungus, which stimulates an immune response against the fungus. Used for Coccidioidomycosis prevention in individuals at high risk.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}