{"id":"sodium-selenite-pentahydrate","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-15%","effect":"Vomiting"},{"rate":"5-10%","effect":"Diarrhea"}]},"_chembl":{"chemblId":"CHEMBL112302","moleculeType":"Small molecule","molecularWeight":"172.94"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Sodium selenite pentahydrate works by donating electrons to reactive oxygen species, thereby neutralizing their harmful effects. This can help to reduce inflammation and oxidative stress, which are associated with various diseases. However, the exact mechanisms of its therapeutic effects are not fully understood.","oneSentence":"Sodium selenite pentahydrate is a selenium compound that acts as an antioxidant and has been investigated for its potential to reduce oxidative stress and inflammation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:35:09.086Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute promyelocytic leukemia"}]},"trialDetails":[{"nctId":"NCT04201561","phase":"PHASE3","title":"High Dose Inorganic Selenium for Preventing Chemotherapy Induced Peripheral Neuropathy","status":"UNKNOWN","sponsor":"Seoul National University Hospital","startDate":"2019-12-24","conditions":"Chemotherapy-induced Peripheral Neuropathy, Recurrent Ovarian Carcinoma, Ovarian Cancer","enrollment":68},{"nctId":"NCT02832648","phase":"PHASE3","title":"Selenium for Musculoskeletal Health","status":"COMPLETED","sponsor":"Sheffield Teaching Hospitals NHS Foundation Trust","startDate":"2017-01","conditions":"Osteoporosis","enrollment":123},{"nctId":"NCT04296578","phase":"PHASE1","title":"Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant Prostate Cancer Progressing on Abiraterone","status":"WITHDRAWN","sponsor":"Stanford University","startDate":"2020-10","conditions":"Prostate Cancer, Castrate Resistant Prostate Cancer","enrollment":""},{"nctId":"NCT01390506","phase":"PHASE2","title":"Selenium to Improve Neurological Outcome After Cardiac Arrest","status":"WITHDRAWN","sponsor":"Medical University of Graz","startDate":"2017-01","conditions":"Cardiac Arrest","enrollment":""},{"nctId":"NCT02026856","phase":"","title":"Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis","status":"COMPLETED","sponsor":"Pavol Jozef Safarik University","startDate":"2013-12","conditions":"Severe Sepsis","enrollment":4}],"_emaApprovals":[],"_faersSignals":[{"count":2,"reaction":"DEVICE RELATED INFECTION"},{"count":1,"reaction":"ANAEMIA"},{"count":1,"reaction":"BRONCHITIS"},{"count":1,"reaction":"ENTERITIS"},{"count":1,"reaction":"HEADACHE"},{"count":1,"reaction":"IRON DEFICIENCY ANAEMIA"},{"count":1,"reaction":"MEDICAL DEVICE SITE INFLAMMATION"},{"count":1,"reaction":"NASOPHARYNGITIS"},{"count":1,"reaction":"NAUSEA"},{"count":1,"reaction":"RASH"}],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Selentab inj. A12CE02"],"phase":"phase_3","status":"active","brandName":"sodium selenite pentahydrate","genericName":"sodium selenite pentahydrate","companyName":"Seoul National University Hospital","companyId":"seoul-national-university-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sodium selenite pentahydrate is a selenium compound that acts as an antioxidant and has been investigated for its potential to reduce oxidative stress and inflammation. Used for Acute promyelocytic leukemia.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}