{"id":"sodium-propionate","rwe":[],"tags":[],"safety":{"boxedWarnings":[],"drugInteractions":[],"commonSideEffects":[],"contraindications":[],"specialPopulations":{}},"trials":[],"_chembl":{"chemblId":"CHEMBL500826","moleculeType":"Small molecule","molecularWeight":"96.06"},"aliases":[],"patents":[],"pricing":[],"offLabel":[],"timeline":[],"_dailymed":{"setId":"4d7691af-f66d-43b1-9d75-eb7bb5295c36","title":"OINKMENT (ETHYL ALCOHOL, SODIUM PROPIONATE) LIQUID [ANIMAL SCIENCE PRODUCTS, INC.]"},"aiSummary":"Sodium propionate is a small molecule with the synonyms E281 and Sodium propionate. It has been studied in various clinical trials, including those for multiple sclerosis, end stage renal disease, and healthy individuals, with interventions such as propionic acid capsules and saline.","ecosystem":[],"mechanism":{"target":"Carbonic anhydrase, Free fatty acid receptor 3","novelty":"Not novel; widely used in food preservation","modality":"Topical/Ingested","drugClass":"Antimicrobial preservative","explanation":"It inhibits the growth of fungi and bacteria by interfering with their cellular metabolism and structural integrity.","oneSentence":"Sodium propionate acts as an antimicrobial agent by disrupting the cell wall and metabolic processes of microorganisms.","technicalDetail":"Sodium propionate lowers the pH inside microbial cells, leading to the disruption of essential cellular functions and ultimately cell death."},"_scrapedAt":"2026-03-28T03:00:32.694Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"commercial":{"yoyGrowth":null,"launchDate":null,"annualCostUS":null,"currentRevenue":null,"patientPopulation":null,"peakSalesEstimate":null},"references":[],"biosimilars":[],"competitors":[],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"indications":{"approved":[],"offLabel":[],"pipeline":[]},"labelChanges":[],"relatedDrugs":[],"trialDetails":[{"nctId":"NCT07498647","phase":"PHASE2","title":"Clinical Trial of BR2251 Tablets for Patients With Primary Gout and Hyperuricemia","status":"NOT_YET_RECRUITING","sponsor":"BioRay Pharmaceutical Co., Ltd.","startDate":"2026-04-01","conditions":"Gout and Hyperuricemia","enrollment":160},{"nctId":"NCT07493226","phase":"NA","title":"Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis","status":"RECRUITING","sponsor":"Konya Beyhekim Training and Research Hospital","startDate":"2026-04-01","conditions":"Frozen Shoulder, Adhesive Capsulitis, Shoulder Pain","enrollment":120},{"nctId":"NCT05275686","phase":"PHASE2","title":"Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)","status":"RECRUITING","sponsor":"Cedars-Sinai Medical Center","startDate":"2022-04-20","conditions":"Eustachian Tube Dysfunction","enrollment":80},{"nctId":"NCT05676489","phase":"EARLY_PHASE1","title":"MeFAMP for Imaging System A Amino Acid Transport in Primary and Metastatic Brain Tumors","status":"NOT_YET_RECRUITING","sponsor":"University of Alabama at Birmingham","startDate":"2026-04-01","conditions":"Healthy Volunteers, Recurrent Glioma, Brain Metastases From Extra-cranial Solid Tumors","enrollment":28},{"nctId":"NCT07318129","phase":"NA","title":"Indole-3-PROpionic Acid Clinical Trials - Multiple Sclerosis","status":"RECRUITING","sponsor":"Glostrup University Hospital, Copenhagen","startDate":"2026-01-26","conditions":"Relapsing Remitting Multiple Sclerosis (RRMS)","enrollment":220},{"nctId":"NCT02029898","phase":"PHASE1, PHASE2","title":"Remifentanil for General Anesthesia in the Context of Immaturity","status":"COMPLETED","sponsor":"University Hospital, Rouen","startDate":"2014-02-02","conditions":"Cesarean Section, Anesthesia","enrollment":53},{"nctId":"NCT06564857","phase":"PHASE4","title":"Remifentanil Versus Rocuronium for Optimizing Video Laryngoscopy-assisted Tracheal Intubation","status":"RECRUITING","sponsor":"Nordsjaellands Hospital","startDate":"2025-11-17","conditions":"Tracheal Intubation, Video Laryngoscopy, Remifentanil","enrollment":2648},{"nctId":"NCT04700527","phase":"PHASE1, PHASE2","title":"The Effects of SCFA Supplementation in Subjects Receiving Abdominopelvic RT: A Randomized Controlled Study","status":"RECRUITING","sponsor":"UNC Lineberger Comprehensive Cancer Center","startDate":"2023-12-15","conditions":"Toxicity, Radiation Toxicity","enrollment":122},{"nctId":"NCT05135702","phase":"NA","title":"Effect of Propionic Acid Supplementation on Endothelial Function","status":"NOT_YET_RECRUITING","sponsor":"Medical College of Wisconsin","startDate":"2027-07","conditions":"Cardiovascular Diseases, Endothelial Dysfunction","enrollment":20},{"nctId":"NCT07105514","phase":"NA","title":"Indole-3-PROpionic Acid Clinical Trials - a Pilot Study Part 2","status":"RECRUITING","sponsor":"Glostrup University Hospital, Copenhagen","startDate":"2025-08-04","conditions":"Healthy","enrollment":32},{"nctId":"NCT01692002","phase":"NA","title":"Oral Propionate to Treat and Prevent Diabetes","status":"TERMINATED","sponsor":"Imperial College London","startDate":"2013-01","conditions":"Diabetes Mellitus","enrollment":6},{"nctId":"NCT06817967","phase":"NA","title":"A Study Comparing Proponent Solution - Nasal Spray (PSNS) With Salt Water for Treating Nasal Congestion Symptoms in Adults With Rebound Nasal Congestion While Weaning From Nasal Decongestant Sprays","status":"COMPLETED","sponsor":"Pharma Nordic AS","startDate":"2024-02-25","conditions":"Rhinitis Medicamentosa","enrollment":194},{"nctId":"NCT06858423","phase":"PHASE4","title":"Budesonide Nasal Irrigation Versus Fluticasone Propionate Nasal Spray in Treating Allergic Rhinitis Patients","status":"COMPLETED","sponsor":"Benha University","startDate":"2023-08-15","conditions":"Nasal Allergy","enrollment":360},{"nctId":"NCT06674018","phase":"NA","title":"Indole-3-PROpionic Acid Clinical Trials - a Pilot Study","status":"COMPLETED","sponsor":"Glostrup University Hospital, Copenhagen","startDate":"2024-11-14","conditions":"Healthy","enrollment":79},{"nctId":"NCT05858437","phase":"NA","title":"Impact of Propionic Acid on Regulatory T Cell Function in Children With CKD","status":"RECRUITING","sponsor":"Charite University, Berlin, Germany","startDate":"2024-01-15","conditions":"CKD (Chronic Kidney Disease) Stage 5D","enrollment":16},{"nctId":"NCT06198374","phase":"NA","title":"Impact of Propionic Acid on Regulatory T Cell Function in Healthy Adults ( Pro-Health)","status":"ACTIVE_NOT_RECRUITING","sponsor":"Charite University, Berlin, Germany","startDate":"2024-01-08","conditions":"Healthy","enrollment":24},{"nctId":"NCT03367533","phase":"PHASE1","title":"Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial","status":"COMPLETED","sponsor":"Yale University","startDate":"2018-11-29","conditions":"Depressive Disorder, Major, Post Traumatic Stress Disorder, Bipolar Disorder","enrollment":13},{"nctId":"NCT05915013","phase":"PHASE1","title":"Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response","status":"RECRUITING","sponsor":"Yale University","startDate":"2023-09-07","conditions":"Depressive Disorder, Major, Post Traumatic Stress Disorder","enrollment":50},{"nctId":"NCT06806826","phase":"PHASE4","title":"The Effect of Omalizumab on Allergic Rhinitis Symptoms: a Comparative Study","status":"COMPLETED","sponsor":"Yuzuncu Yil University","startDate":"2019-01-01","conditions":"Allergic Rhinitis","enrollment":50},{"nctId":"NCT02630121","phase":"PHASE4","title":"Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea","status":"RECRUITING","sponsor":"University of South Florida","startDate":"2023-04-01","conditions":"Sleep Apnea, Chronic Nasal Congestion","enrollment":52},{"nctId":"NCT05576038","phase":"NA","title":"Tryptophan for Impaired AhR Signaling in Celiac Disease","status":"RECRUITING","sponsor":"McMaster University","startDate":"2022-12-01","conditions":"Tryptophan Metabolism Alterations, Celiac Disease","enrollment":50},{"nctId":"NCT02402465","phase":"PHASE4","title":"Factors Involved in Dymista's Superior Clinical Efficacy in the Treatment of Seasonal Allergic Rhinitis","status":"COMPLETED","sponsor":"University of Chicago","startDate":"2015-02","conditions":"Allergic Rhinitis","enrollment":22},{"nctId":"NCT06402487","phase":"PHASE2, PHASE3","title":"Propionic Acid in Multiple Sclerosis","status":"COMPLETED","sponsor":"Salzburger Landeskliniken","startDate":"2024-05-01","conditions":"Multiple Sclerosis","enrollment":101},{"nctId":"NCT03864094","phase":"PHASE4","title":"Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.","status":"COMPLETED","sponsor":"Helse Fonna","startDate":"2022-03-15","conditions":"Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous","enrollment":128},{"nctId":"NCT04093453","phase":"NA","title":"The Acute Effect of Propionate on Energy Homeostasis","status":"COMPLETED","sponsor":"Imperial College London","startDate":"2018-02-12","conditions":"Obesity","enrollment":53},{"nctId":"NCT00489346","phase":"PHASE3","title":"A Study to Evaluate MK0476 and Fluticasone to Control Asthma in Patients With Mild Persistent Asthma (0476-910)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2001-10","conditions":"Asthma, Bronchial","enrollment":994},{"nctId":"NCT00127166","phase":"PHASE3","title":"Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Participants With Asthma (0476-911)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2005-12","conditions":"Exercise Induced Asthma","enrollment":154},{"nctId":"NCT00284856","phase":"PHASE3","title":"Montelukast Asthmatic Smoker Study (0476-332)(COMPLETED)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2006-05","conditions":"Asthma","enrollment":1640},{"nctId":"NCT03554317","phase":"PHASE2","title":"COMbination of Bipolar Androgen Therapy and Nivolumab","status":"COMPLETED","sponsor":"Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins","startDate":"2018-09-05","conditions":"Castration-resistant Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer","enrollment":45},{"nctId":"NCT03987126","phase":"PHASE3","title":"Prebiotics for Spinal Cord Injury Patients With Bowel and Bladder Dysfunction","status":"COMPLETED","sponsor":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","startDate":"2021-01-27","conditions":"Spinal Cord Injuries, Neurogenic Bowel, Bladder Dysfunction","enrollment":30},{"nctId":"NCT05839366","phase":"PHASE3","title":"Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients","status":"UNKNOWN","sponsor":"Nanfang Hospital, Southern Medical University","startDate":"2023-05-31","conditions":"Septic Shock, Mechanical Ventilation Complication","enrollment":124},{"nctId":"NCT06084624","phase":"PHASE1, PHASE2","title":"Evaluation of Topical Rebamipide Versus Topical Betamethasone for Management of Oral Ulcers in Behcet's Disease","status":"UNKNOWN","sponsor":"Cairo University","startDate":"2023-12","conditions":"Oral Ulceration Due to Behçet's Disease","enrollment":40},{"nctId":"NCT03994146","phase":"PHASE4","title":"Remifentanil Tapering and Post-adenotonsillectomy Pain in Children","status":"TERMINATED","sponsor":"University Hospital, Akershus","startDate":"2020-01-16","conditions":"Child, Only, Pain, Tonsillectomy","enrollment":6},{"nctId":"NCT02689024","phase":"PHASE4","title":"Delirium in Elderly Patients With Trauma of the Hip","status":"TERMINATED","sponsor":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","startDate":"2016-05","conditions":"Hip Fractures, Anesthesia","enrollment":239},{"nctId":"NCT04153396","phase":"PHASE4","title":"Preemptive Infiltration With Betamethasone and Ropivacaine for Postoperative Pain in Laminoplasty or Laminectomy","status":"COMPLETED","sponsor":"Beijing Tiantan Hospital","startDate":"2021-09-01","conditions":"Pain, Postoperative, Neurosurgery","enrollment":116},{"nctId":"NCT05706454","phase":"PHASE2, PHASE3","title":"Phase 2/Phase 3 Study To Evaluate The Efficacy And Safety Of Ramatroban Along With The Standard Of Care In Subjects Hospitalized For COVID Pneumonia","status":"RECRUITING","sponsor":"KARE Biosciences","startDate":"2022-11-10","conditions":"COVID-19 Pneumonia, COVID-19 Respiratory Infection","enrollment":324},{"nctId":"NCT04991714","phase":"EARLY_PHASE1","title":"Effect of Sweetness Intensity of a Sucrose Solution on Blood Glucose Regulation and Energy Intake","status":"COMPLETED","sponsor":"University of Vienna","startDate":"2021-08-05","conditions":"Blood Glucose, Low, Hunger","enrollment":30},{"nctId":"NCT05468671","phase":"PHASE4","title":"Clinical Application Value of Remazolam Combined With Sugammadex Sodium in Anesthesia for Endotracheal Surgery Under Bronchoscopy","status":"COMPLETED","sponsor":"Zhejiang Cancer Hospital","startDate":"2021-01-04","conditions":"Endobronchial Metastases, Bronchoesophageal Fistula, General Anesthetic Drug Adverse Reaction","enrollment":34},{"nctId":"NCT03978208","phase":"PHASE2","title":"Efficacy and Safety of ATB-346 Versus Placebo in Osteoarthritis Patients","status":"COMPLETED","sponsor":"Antibe Therapeutics Inc.","startDate":"2019-03-29","conditions":"Osteoarthritis","enrollment":381},{"nctId":"NCT04260412","phase":"NA","title":"The Effect of Combining Medium Cut Off Dialysis Membrane and Diet Modification on Reducing of Inflammation Response","status":"UNKNOWN","sponsor":"University Medical Centre Ljubljana","startDate":"2020-08-31","conditions":"End Stage Renal Disease, Haemodialysis, Diet, Healthy","enrollment":50},{"nctId":"NCT04247867","phase":"NA","title":"Combination of Medium Cut-off Dialyzer Membrane and Diet Modification to Alleviate Residual Uremic Syndrome of Dialysis Patients","status":"UNKNOWN","sponsor":"University Medical Centre Ljubljana","startDate":"2020-08-31","conditions":"End Stage Renal Disease, Haemodialysis, Diet, Healthy","enrollment":50},{"nctId":"NCT05318521","phase":"PHASE3","title":"RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee","status":"UNKNOWN","sponsor":"Overseas Pharmaceuticals, Ltd.","startDate":"2021-12-10","conditions":"Degenerative Arthritis","enrollment":500},{"nctId":"NCT00540839","phase":"PHASE3","title":"A Study of Montelukast (MK-0476) Compared With Fluticasone in Pediatric Participants With Chronic Asthma (MK-0476-303)","status":"WITHDRAWN","sponsor":"Organon and Co","startDate":"2007-11","conditions":"Asthma, Bronchial","enrollment":""},{"nctId":"NCT02553265","phase":"PHASE2","title":"Carbidopa for the Treatment of Excessive Blood Pressure Variability","status":"COMPLETED","sponsor":"NYU Langone Health","startDate":"2015-09","conditions":"Dysautonomia, Familial, Baroreflex Failure Syndrome","enrollment":22},{"nctId":"NCT05115578","phase":"","title":"Remifentanil Effect-site Prediction by Algometry","status":"COMPLETED","sponsor":"Hospital Universitari Vall d'Hebron Research Institute","startDate":"2017-03-01","conditions":"Conscious Sedation Failure During Procedure","enrollment":100},{"nctId":"NCT03096730","phase":"NA","title":"Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia","status":"COMPLETED","sponsor":"Tianjin Medical University General Hospital","startDate":"2017-02-06","conditions":"Pain, Anesthesia","enrollment":150},{"nctId":"NCT01898884","phase":"PHASE1","title":"Safety and Pharmacology Study of VP 20629 in Adults With Friedreich's Ataxia","status":"COMPLETED","sponsor":"Shire","startDate":"2013-08-13","conditions":"Friedreich's Ataxia","enrollment":46},{"nctId":"NCT04865562","phase":"PHASE4","title":"Hormones and Decision Making","status":"COMPLETED","sponsor":"University of Texas at Austin","startDate":"2015-03-01","conditions":"Dyssocial Behavior","enrollment":30},{"nctId":"NCT02361190","phase":"NA","title":"Effects of Fast Acting Testosterone Nasal Spray on Anxiety","status":"COMPLETED","sponsor":"University of Texas at Austin","startDate":"2015-02","conditions":"Anxiety","enrollment":96},{"nctId":"NCT04242368","phase":"PHASE2, PHASE3","title":"Hypertonic Versus Isotonic Saline Irrigations for Chronic Rhinosinusitis","status":"WITHDRAWN","sponsor":"Stanford University","startDate":"2020-07-01","conditions":"Chronic Rhinosinusitis (Diagnosis)","enrollment":""},{"nctId":"NCT04066426","phase":"PHASE4","title":"Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain","status":"COMPLETED","sponsor":"Yuzuncu Yil University","startDate":"2018-03-01","conditions":"Temporomandibular Disorder","enrollment":200},{"nctId":"NCT03590496","phase":"NA","title":"Safety and Efficacy of Propionate for Reduction of LDL Cholesterol","status":"COMPLETED","sponsor":"Charite University, Berlin, Germany","startDate":"2018-07-25","conditions":"Hypercholesterolemia","enrollment":62},{"nctId":"NCT03912740","phase":"NA","title":"Effect of Dexmedetomidine on Nol-Index Guided Remifentanil Analgesia","status":"COMPLETED","sponsor":"Erasme University Hospital","startDate":"2019-04-11","conditions":"Nociceptive Pain, Anesthesia, Opioid Use","enrollment":58},{"nctId":"NCT00756717","phase":"PHASE4","title":"Study Of MK-0752 In Combination With Tamoxifen Or Letrozole to Treat Early Stage Breast Cancer","status":"COMPLETED","sponsor":"Loyola University","startDate":"2008-02-14","conditions":"Breast Cancer","enrollment":22},{"nctId":"NCT03963700","phase":"","title":"Tumor Characteristics in Patients With Paraneoplastic Neurological Syndromes (PNS)","status":"UNKNOWN","sponsor":"Hospices Civils de Lyon","startDate":"2019-02-01","conditions":"Cancer, Paraneoplastic Syndromes, Neurologic Disorder","enrollment":980},{"nctId":"NCT01243762","phase":"PHASE1","title":"A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)","status":"TERMINATED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2010-11-22","conditions":"Neoplasms Malignant","enrollment":47},{"nctId":"NCT03291418","phase":"PHASE1, PHASE2","title":"To Compare the Gastrointestinal Safety of a 14-Day Oral Dosing Regimen of ATB-346 to Sodium Naproxen in Healthy Subjects","status":"COMPLETED","sponsor":"Antibe Therapeutics Inc.","startDate":"2017-09-08","conditions":"Gastric Ulcer","enrollment":258},{"nctId":"NCT03508102","phase":"NA","title":"Effect of Remifentanil on the Bispectral Index in Women Undergoing Caesarean Delivery Under General Anaesthesia","status":"COMPLETED","sponsor":"West China Second University Hospital","startDate":"2015-08","conditions":"Intraoperative Awareness","enrollment":60},{"nctId":"NCT02403687","phase":"","title":"Prospective Analgesic Compound Efficacy (PACE) Study","status":"COMPLETED","sponsor":"Express Specialty Pharmacy","startDate":"2015-06","conditions":"Arthritis, Tendonitis, Gout","enrollment":300},{"nctId":"NCT00843193","phase":"PHASE2","title":"Efficacy and Safety Study of GSK679586 in Patients With Severe Asthma","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2008-12-09","conditions":"Asthma","enrollment":198},{"nctId":"NCT03283020","phase":"PHASE4","title":"Opioid-Induced Swallowing Dysfunction - The Impact of Bolus Volume","status":"UNKNOWN","sponsor":"Region Örebro County","startDate":"2017-11-11","conditions":"Pharyngeal Dysfunction, Pharyngeal Swallowing","enrollment":20},{"nctId":"NCT02463383","phase":"EARLY_PHASE1","title":"Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women","status":"COMPLETED","sponsor":"Professor Lars Ove Dragsted","startDate":"2013-09","conditions":"Breast Cancer","enrollment":25},{"nctId":"NCT02208778","phase":"PHASE4","title":"Imaging Pain Relief in Osteoarthritis","status":"COMPLETED","sponsor":"University of Nottingham","startDate":"2014-12","conditions":"Osteoarthritis, Chronic Pain","enrollment":77},{"nctId":"NCT03110653","phase":"NA","title":"Remifentanil and Hyperalgesia: Gradual Withdrawal Versus Immediate Discontinuation","status":"COMPLETED","sponsor":"Université Libre de Bruxelles","startDate":"2017-04-15","conditions":"Anesthesia, Pain","enrollment":30},{"nctId":"NCT01307462","phase":"PHASE2","title":"Targeted Therapy of Bronchiolitis Obliterans Syndrome","status":"COMPLETED","sponsor":"Stephanie Lee","startDate":"2011-06","conditions":"Bronchiolitis Obliterans","enrollment":36},{"nctId":"NCT03251066","phase":"NA","title":"Immediate Effect of Proponent-Nasal-Spray on Unspecific Discomfort in the Nose","status":"COMPLETED","sponsor":"PRECLIN Biosystems AG","startDate":"2017-04-27","conditions":"Unspecified Disorder of Nose and Nasal Sinuses","enrollment":54},{"nctId":"NCT03231683","phase":"PHASE2","title":"Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal Hysterectomy","status":"COMPLETED","sponsor":"KK Women's and Children's Hospital","startDate":"2014-03","conditions":"Ketamine, Anesthesia, Morphine","enrollment":90},{"nctId":"NCT02809378","phase":"PHASE4","title":"The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of PONV","status":"COMPLETED","sponsor":"Ajou University School of Medicine","startDate":"2016-06","conditions":"PONV, Palonosetron, Anesthesia","enrollment":150},{"nctId":"NCT03220633","phase":"PHASE1","title":"Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects","status":"COMPLETED","sponsor":"Antibe Therapeutics Inc.","startDate":"2014-06","conditions":"Chronic Pain","enrollment":84},{"nctId":"NCT01893879","phase":"NA","title":"Placebo-Controlled Therapeutic Trial for the Prevention of Lymphedema","status":"TERMINATED","sponsor":"Stanford University","startDate":"2014-04","conditions":"Lymphedema, Unspecified Adult Solid Tumor, Protocol Specific","enrollment":14},{"nctId":"NCT01712685","phase":"PHASE2","title":"Imaging Studies of Kidney Cancer Using 18F-VM4-037","status":"TERMINATED","sponsor":"National Cancer Institute (NCI)","startDate":"2012-10","conditions":"Carcinoma, Renal Cell, Kidney Neoplasms","enrollment":12},{"nctId":"NCT02976688","phase":"PHASE2, PHASE3","title":"Effects of Short-chain Fatty Acids on Inflammatory and Metabolic Parameters in Maintenance Hemodialysis","status":"UNKNOWN","sponsor":"Azienda Sanitaria ASL Avellino 2","startDate":"2017-01","conditions":"Endstage Renal Disease","enrollment":15},{"nctId":"NCT01592162","phase":"PHASE4","title":"Comparison of Different Propofol Formulations With or Without Remifentanil","status":"COMPLETED","sponsor":"Hopital Foch","startDate":"2013-05","conditions":"Anesthesia","enrollment":409},{"nctId":"NCT00533650","phase":"PHASE2","title":"Proof of Concept (Bone Resorption/Bone Mineral Density) Study (0429-005)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2000-12","conditions":"Post-Menopausal Osteoporosis","enrollment":227},{"nctId":"NCT00803894","phase":"PHASE1","title":"A Clinical Study to Determine Biomarkers of Response to a Gamma Secretase Inhibitor","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2008-12","conditions":"Healthy","enrollment":30},{"nctId":"NCT02569905","phase":"PHASE4","title":"Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering","status":"COMPLETED","sponsor":"Guangxi Medical University","startDate":"2014-04","conditions":"Postoperative Shivering","enrollment":166},{"nctId":"NCT01098344","phase":"PHASE1","title":"MK0752 and Gemcitabine Hydrochloride in Treating Patients With Stage III and IV Pancreatic Cancer That Cannot Be Removed by Surgery","status":"COMPLETED","sponsor":"Cancer Research UK","startDate":"2010-04","conditions":"Pancreatic Cancer","enrollment":44},{"nctId":"NCT01295632","phase":"PHASE1","title":"Safety and Tolerability of Different Dose Combinations of Ridaforolimus With MK-2206 or MK-0752 for Participants With Advanced Cancer (MK-8669-049)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2011-02","conditions":"Advanced Cancer","enrollment":65},{"nctId":"NCT02486926","phase":"NA","title":"The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children","status":"COMPLETED","sponsor":"Hallym University Medical Center","startDate":"2012-11","conditions":"Adverse Effect of Other General Anesthetics","enrollment":102},{"nctId":"NCT00100152","phase":"PHASE1","title":"A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013)","status":"TERMINATED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2005-02","conditions":"Leukemia, Lymphoblastic, Acute, T-cell, Myelogenous Leukemia, Chronic Lymphocytic Leukemia","enrollment":50},{"nctId":"NCT00272467","phase":"PHASE4","title":"Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy","status":"COMPLETED","sponsor":"Korea Otsuka International Asia Arab","startDate":"2005-07","conditions":"Stomach Ulcer","enrollment":132},{"nctId":"NCT01757379","phase":"NA","title":"Determination of the Bioavailability of Short Chain Fatty Acids in Healthy Humans","status":"COMPLETED","sponsor":"KU Leuven","startDate":"2011-04","conditions":"Short Chain Fatty Acids Bioavailability","enrollment":12},{"nctId":"NCT02271555","phase":"PHASE4","title":"The Effects of Remifentanil on Attenuating the Hemodynamic Responses After Electroconvulsive Therapy","status":"UNKNOWN","sponsor":"Inonu University","startDate":"2014-10","conditions":"Haemodynamic Rebound","enrollment":58},{"nctId":"NCT01889446","phase":"NA","title":"The Effects of the Food Preservative Propionic Acid in Post-prandial Metabolism","status":"UNKNOWN","sponsor":"Brigham and Women's Hospital","startDate":"2013-08","conditions":"Obesity, Insulin Resistance, Diabetes","enrollment":20},{"nctId":"NCT00645333","phase":"PHASE1, PHASE2","title":"Phase I/II Study of MK-0752 Followed by Docetaxel in Advanced or Metastatic Breast Cancer","status":"COMPLETED","sponsor":"University of Michigan Rogel Cancer Center","startDate":"2008-03","conditions":"Metastatic Breast Cancer","enrollment":30},{"nctId":"NCT02104297","phase":"PHASE4","title":"Effect of Deksmedetomidine and Remifentanil in Extubation Agitation","status":"UNKNOWN","sponsor":"Diskapi Yildirim Beyazit Education and Research Hospital","startDate":"2014-04","conditions":"Agitation","enrollment":90},{"nctId":"NCT02093143","phase":"PHASE3","title":"Conditions of Diagnostic Panendoscopy of the Upper Airway Under Propofol Remifentanil General Anesthesia","status":"COMPLETED","sponsor":"Centre Hospitalier Universitaire de Besancon","startDate":"2009-06","conditions":"Tumor of Ear, Nose and Throat","enrollment":256},{"nctId":"NCT00935142","phase":"PHASE1","title":"Non-invasive Imaging With [18F]VM4-037","status":"WITHDRAWN","sponsor":"Maastricht Radiation Oncology","startDate":"2012-01","conditions":"Stage 4 Cancer","enrollment":""},{"nctId":"NCT01758913","phase":"NA","title":"Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants","status":"COMPLETED","sponsor":"Taipei Medical University Hospital","startDate":"2007-02","conditions":"Patent Ductus Arteriosus","enrollment":110},{"nctId":"NCT00169559","phase":"PHASE2","title":"Dyslipidemia Study Investigating The Increase In \"Good Cholesterol\"","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2003-11","conditions":"Dyslipidaemias","enrollment":250},{"nctId":"NCT01495377","phase":"PHASE4","title":"Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration","status":"COMPLETED","sponsor":"Region Örebro County","startDate":"2012-01","conditions":"Opioid Induced Swallowing Disorders","enrollment":25},{"nctId":"NCT00388180","phase":"","title":"An Exploratory Study To Look At The Effect Of Two Investigational Drugs On Body Fat And Inflammation","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2004-12","conditions":"Hypercholesterolemia, Dyslipidaemias, Obesity","enrollment":71},{"nctId":"NCT00572182","phase":"PHASE1","title":"MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer","status":"TERMINATED","sponsor":"Pediatric Brain Tumor Consortium","startDate":"2008-07","conditions":"Brain and Central Nervous System Tumors","enrollment":33},{"nctId":"NCT01191645","phase":"PHASE4","title":"Opioid Effects on Swallowing and Esophageal Sphincter Pressure","status":"COMPLETED","sponsor":"Region Örebro County","startDate":"2010-10","conditions":"Opioid Induced Pharyngeal and Esophageal Dysfunction","enrollment":14},{"nctId":"NCT00813098","phase":"PHASE2","title":"Study of LX1031 in Subjects With Non-Constipating Irritable Bowel Syndrome","status":"COMPLETED","sponsor":"Lexicon Pharmaceuticals","startDate":"2008-12","conditions":"Irritable Bowel Syndrome","enrollment":155},{"nctId":"NCT00884520","phase":"EARLY_PHASE1","title":"An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037","status":"COMPLETED","sponsor":"Siemens Molecular Imaging","startDate":"2009-04","conditions":"Lung Cancer, Squamous Cell Carcinoma, Head and Neck Cancer","enrollment":16},{"nctId":"NCT01013558","phase":"PHASE1","title":"New Options for Preoperative Anesthesia in Intrauterine Needling","status":"COMPLETED","sponsor":"Leiden University Medical Center","startDate":"2004-09","conditions":"Stress, Pain","enrollment":50},{"nctId":"NCT00567957","phase":"PHASE4","title":"Remifentanil for General Anesthesia in Preeclamptics","status":"UNKNOWN","sponsor":"Istanbul University","startDate":"2008-02","conditions":"Pre-Eclampsia, Hypertension, Pregnancy-Induced, Pregnancy Complications","enrollment":50}],"_emaApprovals":[],"_faersSignals":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"formularyStatus":[],"_approvalHistory":[],"developmentCodes":[],"ownershipHistory":[],"publicationCount":476,"therapeuticAreas":["Metabolic"],"biosimilarFilings":[],"companionDiagnostics":[],"genericManufacturerList":[],"phase":"marketed","status":"active","brandName":"SODIUM PROPIONATE","genericName":"SODIUM PROPIONATE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"trialStats":{"total":1,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}