{"id":"sodium-phosphates-in-plastic-container","_fda":{"id":"848ca4be-1f89-b274-e053-2a91aa0ad774","set_id":"01ddf3ee-e925-404d-9b41-7876d5fd6634","openfda":{"nui":["N0000185375","N0000185371","N0000175629","N0000184306","M0000728","M0006342","M0016962","M0022575","N0000185001","M0516536"],"upc":["0361727331212"],"unii":["00UK7646FG","7TPC058OWY","QDL83WN8C2","70WT22SF4B","269XH13919","70FD1KFU70"],"route":["SUBLINGUAL"],"spl_id":["848ca4be-1f89-b274-e053-2a91aa0ad774"],"brand_name":["Acid Reflux Relief"],"spl_set_id":["01ddf3ee-e925-404d-9b41-7876d5fd6634"],"package_ndc":["61727-331-21"],"product_ndc":["61727-331"],"generic_name":["CAPSICUM, SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, STRYCHNOS NUX-VOMICA SEED, ROBINIA PSEUDOACACIA BARK, SULFUR, SEPIA OFFICINALIS JUICE"],"product_type":["HUMAN OTC DRUG"],"pharm_class_cs":["Allergens [CS]","Dietary Proteins [CS]","Plant Proteins [CS]","Vegetable Proteins [CS]","Seed Storage Proteins [CS]"],"pharm_class_pe":["Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"substance_name":["CAPSICUM","ROBINIA PSEUDOACACIA BARK","SEPIA OFFICINALIS JUICE","SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE","STRYCHNOS NUX-VOMICA SEED","SULFUR"],"pharm_class_epc":["Non-Standardized Plant Allergenic Extract [EPC]","Non-Standardized Food Allergenic Extract [EPC]"],"manufacturer_name":["Homeocare Laboratories"],"is_original_packager":[true]},"purpose":["Purpose: For the temporary relief of heartburns, acid reflux and dyspepsia."],"version":"2","warnings":["Warnings: If symptoms persist or worsen, or if pregnant or nursing, consult a doctor. Keep out of reach of children. Do not use if cap seal is broken or missing."],"effective_time":"20190320","active_ingredient":["Active Ingredients: Capiscuum Annuun 7C, Natrum Phos 6X, Nux Vomica 9C, Robinia Pseudaccia 9C, Sulphur 5C, Sepia 5C."],"inactive_ingredient":["Inactive Ingredients: Sucrose/lactose."],"indications_and_usage":["Indications & Usage: Turn tube upside down, twist cap to break seal & release pellets. Using clear cap, place 3 pellets to dissolve under your tongue before meals or as needed. Take apart from food or drinks. To preserve purity avoid touching pellets with fingers."],"dosage_and_administration":["Dosage & Administration: Turn tube upside down, twist cap to break seal & release pellets. Using clear cap, place 3 pellets to dissolve under your tongue before meals or as needed. Take apart from food or drinks. To preserve purity avoid touching pellets with fingers."],"spl_product_data_elements":["Acid Reflux Relief CAPSICUM, SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE, STRYCHNOS NUX-VOMICA SEED, ROBINIA PSEUDOACACIA BARK, SULFUR, SEPIA OFFICINALIS JUICE SUCROSE LACTOSE CAPSICUM CAPSICUM SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE PHOSPHATE ION STRYCHNOS NUX-VOMICA SEED STRYCHNOS NUX-VOMICA SEED ROBINIA PSEUDOACACIA BARK ROBINIA PSEUDOACACIA BARK SULFUR SULFUR SEPIA OFFICINALIS JUICE SEPIA OFFICINALIS JUICE"],"keep_out_of_reach_of_children":["Keep out of reach of children. Keep out of reach of children."],"package_label_principal_display_panel":["Acid Reflux Relief hcl_label_acidRlx-2012.jpg"]},"safety":{"boxedWarnings":[],"safetySignals":[{"date":"","signal":"FATIGUE","source":"FDA FAERS","actionTaken":"166 reports"},{"date":"","signal":"NAUSEA","source":"FDA FAERS","actionTaken":"148 reports"},{"date":"","signal":"DIARRHOEA","source":"FDA FAERS","actionTaken":"131 reports"},{"date":"","signal":"DIZZINESS","source":"FDA FAERS","actionTaken":"131 reports"},{"date":"","signal":"PAIN","source":"FDA FAERS","actionTaken":"131 reports"},{"date":"","signal":"HEADACHE","source":"FDA FAERS","actionTaken":"130 reports"},{"date":"","signal":"ARTHRALGIA","source":"FDA FAERS","actionTaken":"108 reports"},{"date":"","signal":"DRUG INEFFECTIVE","source":"FDA FAERS","actionTaken":"102 reports"},{"date":"","signal":"PAIN IN EXTREMITY","source":"FDA FAERS","actionTaken":"93 reports"},{"date":"","signal":"DYSPNOEA","source":"FDA FAERS","actionTaken":"92 reports"}],"drugInteractions":[{"drug":"Antacids","action":"Avoid","effect":"Decreased absorption of sodium phosphate"},{"drug":"Calcium supplements","action":"Avoid","effect":"Decreased absorption of sodium phosphate"},{"drug":"Magnesium-containing antacids","action":"Monitor","effect":"Increased risk of hypermagnesemia"},{"drug":"Potassium-containing medications","action":"Monitor","effect":"Increased risk of hyperkalemia"},{"drug":"Tetracyclines","action":"Avoid","effect":"Decreased absorption of tetracyclines"},{"drug":"Quinolones","action":"Avoid","effect":"Decreased absorption of quinolones"},{"drug":"Iron supplements","action":"Avoid","effect":"Decreased absorption of iron"},{"drug":"Corticosteroids","action":"Monitor","effect":"Increased risk of hypokalemia"},{"drug":"Diuretics","action":"Monitor","effect":"Increased risk of hypokalemia"},{"drug":"Laxatives","action":"Monitor","effect":"Increased risk of hypokalemia"}],"commonSideEffects":[{"effect":"Visual Acuity Reduced","drugRate":"66.7%","placeboRate":"","totalAtRisk":3,"totalAffected":2,"trialsReporting":1},{"effect":"Ocular Hypertension","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Back Pain","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Hypoaesthesia","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Infection","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Posterior Capsule Opacification","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Vomiting","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Weight Decreased","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Eye Pain","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Limb Injury","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Vitreous Haemorrhage","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Upper Respiratory Tract Inflammation","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Pyrexia","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Corneal Abrasion","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Keratopathy","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Corneal Erosion","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Corneal Neovascularization","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Blood Pressure Increased","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Retinal Haemorrhage","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Von Hippel-Lindau Disease","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Haemangioma of Retina","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Iris Adhesions","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Eye Laser Surgery","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Eye Haemorrhage","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1},{"effect":"Iris Neovascularisation","drugRate":"33.3%","placeboRate":"","totalAtRisk":3,"totalAffected":1,"trialsReporting":1}],"contraindications":["Sodium phosphate is contraindicated in diseases where high phosphorus or low calcium levels may be encountered, and in patients with hypernatremia."],"specialPopulations":{"Pregnancy":"Animal reproduction studies have not been conducted with sodium phosphate. It is also not known whether sodium phosphate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium phosphate should be given to a pregnant woman only if clearly needed.","Geriatric use":"An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, concomitant disease or other drug therapy.","Paediatric use":"The safety and effectiveness of sodium phosphate has been established in pediatric patients (neonates, infants, children, and adolescents).","Renal impairment":"Sodium ions and phosphorus are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.","Hepatic impairment":"An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, concomitant disease or other drug therapy."}},"company":"Pfizer","patents":[{"source":"DrugCentral Orange Book","expires":"2028-06-22","patentNumber":"7687075"}],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Sodium Phosphate, Dibasic, Heptahydrate","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-19T23:49:02.168931+00:00"},"patents":{"url":"","method":"deterministic","source":"FDA Orange Book","rawText":"","confidence":1,"sourceType":"fda_orange_book","retrievedAt":"2026-04-19T23:49:02.168835+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-19T23:49:07.964097+00:00"},"regulatory.eu":{"url":"","method":"api_direct","source":"European Medicines Agency","rawText":"","confidence":1,"sourceType":"ema_api","retrievedAt":"2026-04-19T23:49:02.236826+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Sodium Phosphate, Dibasic, Heptahydrate","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-19T23:49:08.292617+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T23:49:00.840327+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T23:49:00.840363+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T23:49:00.840369+00:00"},"safety.safetySignals":{"url":"https://api.fda.gov/drug/event.json","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-19T23:49:10.413056+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL1060/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-19T23:49:09.588552+00:00"}},"allNames":"acid reflux relief","synonyms":["sodium phosphate, monobasic anhydrous","disodium phosphate","sodium phosphate","sodium phosphate, dibasic, heptahydrate","sodium phosphate, dibasic","sodium phosphate, dibasic anhydrous","sodium phosphate, monobasic, anhydrous"],"timeline":[],"_dailymed":{"setId":"5e405437-6202-418a-8fbb-8b1d9bd9f714","title":"TONICPET 10 (SODIUM PHOSPHATE, DIBASIC, HEPTAHYDRATE) PELLET [GROUPE CYRENNE INC.]","labeler":""},"aiSummary":"Sodium Phosphate, Dibasic, Heptahydrate is a marketed drug by Pfizer Inc. It is used to preserve purity and is taken under the tongue before meals or as needed. The exact mechanism of action is not specified on Wikipedia. This drug has 2 trials and 6 publications. It is a significant commercial entity with $63.6B in revenue. There is limited information available on its clinical differentiation and pipeline developments.","brandName":"Acid Reflux Relief","mechanism":{"target":"Carbonic anhydrase 4","novelty":"me-too","targets":[{"gene":"CA4","source":"DrugCentral","target":"Carbonic anhydrase 4","protein":"Carbonic anhydrase 4","activityType":"Ki"}],"modality":"small molecule","drugClass":"Non-Standardized Plant Allergenic Extract [EPC]","explanation":"","oneSentence":"","technicalDetail":"Sodium Phosphate, Dibasic, Heptahydrate is a sodium salt of the dibasic phosphate ion. It is used to preserve the purity of the drug by stabilizing its chemical structure. The exact mechanism of action is not specified on Wikipedia, but it is believed to work by preventing the degradation of the drug's active ingredients."},"_companyIR":{"url":"https://www.pfizer.com/investors","revenueRefs":[],"pipelineRefs":[]},"commercial":{"yoyGrowth":"7%","launchDate":"1983","annualCostUS":"$80,000/yr","_launchSource":"DrugCentral (FDA 1983-05-10, HOSPIRA)","currentRevenue":"","peakSalesEstimate":""},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4219","fields":["approvals","synonyms","ATC","pharmacokinetics","patents","indications","contraindications","interactions","targets"],"source":"DrugCentral"},{"id":2,"url":"https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Sodium Phosphate, Dibasic, Heptahydrate","fields":["mechanism","safety","indications","administration"],"source":"FDA Drug Label (DailyMed)"},{"id":3,"url":"https://clinicaltrials.gov/search?intr=Sodium%20Phosphate%2C%20Dibasic%2C%20Heptahydrate","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":4,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Sodium Phosphate, Dibasic, Heptahydrate","fields":["publications"],"source":"PubMed/NCBI"},{"id":5,"url":"https://www.ebi.ac.uk/chembl/","fields":["molecular"],"source":"ChEMBL (EMBL-EBI)"},{"id":6,"url":"https://www.ema.europa.eu/","fields":["regulatoryStatus"],"source":"European Medicines Agency (EMA)"},{"id":7,"url":"https://www.whocc.no/atc_ddd_index/","fields":["classification"],"source":"WHO ATC/DDD Index"},{"id":8,"url":"https://list.essentialmeds.org/","fields":["regulatoryStatus"],"source":"WHO Essential Medicines List"}],"_tgaChecked":true,"_validation":{"fieldsValidated":2,"lastValidatedAt":"2026-04-20T08:33:40.475679+00:00","fieldsConflicting":0,"overallConfidence":0.95},"_whoChecked":true,"competitors":[{"name":"Calm Mood","slug":"garlic-avena-sativa-flowering-top-angelica-archangelica-root-arabica-coffee-bean-holy-basil-leaf-passiflora-edulis-flower-scutellaria-lateriflora-whole-verbena-hastata-top-and-macropiper-methysticum-root","company":"Forces of Nature","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"GARLIC, AVENA SATIVA FLOWERING TOP, ANGELICA ARCHANGELICA ROOT, ARABICA COFFEE BEAN, HOLY BASIL LEAF, PASSIFLORA EDULIS FLOWER, SCUTELLARIA LATERIFLORA WHOLE, VERBENA HASTATA TOP, AND MACROPIPER METHYSTICUM ROOT"},{"name":"Histastat Pollen","slug":"baptisia-tinctoria-echinacea-(angustifolia)-adrenalinum-allium-cepa-ambrosia-artemisiaefolia-arsenicum-album-euphrasia-officinalis-histaminum-hydrochloricum-natrum-muriaticum-natrum-sulphuricum-nux-vomica-phosphorus-pulsatilla-(pratensis)-sabadilla-sinapis-nigra-solidago-virgaurea-sulphur-wyethia-helenioides","company":"Energique, Inc.","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"BAPTISIA TINCTORIA, ECHINACEA (ANGUSTIFOLIA), ADRENALINUM, ALLIUM CEPA, AMBROSIA ARTEMISIAEFOLIA, ARSENICUM ALBUM, EUPHRASIA OFFICINALIS, HISTAMINUM HYDROCHLORICUM, NATRUM MURIATICUM, NATRUM SULPHURICUM, NUX VOMICA, PHOSPHORUS, PULSATILLA (PRATENSIS), SABADILLA, SINAPIS NIGRA, SOLIDAGO VIRGAUREA, SULPHUR, WYETHIA HELENIOIDES"},{"name":"Cough and Bronchial Nighttime Syrup","slug":"aconitum-napellus-bryonia-root-calcium-cation-spongia-officinalis-skeleton-roasted-tin-medicago-sativa-leaf-oat-arabica-coffee-bean","company":"Schwabe Mexico S.A. DE C.V.","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"ACONITUM NAPELLUS, BRYONIA ROOT, CALCIUM CATION, SPONGIA OFFICINALIS SKELETON, ROASTED, TIN, MEDICAGO SATIVA LEAF, OAT, ARABICA COFFEE BEAN"},{"name":"Sick Stopper","slug":"echinacea-aconitum-napellus-agaricus-muscarius-aralia-quinquefolia-baptisia-tinctoria-bryonia-chelidonium-majus-eupatorium-perfoliatum-hepar-sulphuris-calcareum-lachesis-mutus-lycopodium-clavatum-rhus-toxicodendron-sanguinaria-canadensis-sulphur-thuja-occidentalis-bufo-rana-nux-vomica-anthracinum-influenzinum-pyrogenium","company":"Newton Laboratories, Inc.","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"ECHINACEA, ACONITUM NAPELLUS, AGARICUS MUSCARIUS, ARALIA QUINQUEFOLIA, BAPTISIA TINCTORIA, BRYONIA, CHELIDONIUM MAJUS, EUPATORIUM PERFOLIATUM, HEPAR SULPHURIS CALCAREUM, LACHESIS MUTUS, LYCOPODIUM CLAVATUM, RHUS TOXICODENDRON, SANGUINARIA CANADENSIS, SULPHUR, THUJA OCCIDENTALIS, BUFO RANA, NUX VOMICA, ANTHRACINUM, INFLUENZINUM, PYROGENIUM"},{"name":"Allergies","slug":"apis-mellifica-echinacea-hydrastis-canadensis-taraxacum-officinale-aconitum-napellus-aethusa-cynapium-agaricus-muscarius-aletris-farinosa-alfalfa-allium-cepa-allium-sativum-ambrosia-artemisiaefolia-arsenicum-album-artemisia-vulgaris-arundo-mauritanica-avena-sativa-belladonna-bellis-perrenis-bovista-bromium-bryonia-caffeinum-calcarea-carbonica-calluna-vulgaris-flos-capsicum-annuum-cat-hair-chamomilla-chelidonium-majus-chenopodium-anthelminticum-cinnamomum","company":"Newton Laboratories, Inc.","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"APIS MELLIFICA, ECHINACEA, HYDRASTIS CANADENSIS, TARAXACUM OFFICINALE, ACONITUM NAPELLUS, AETHUSA CYNAPIUM, AGARICUS MUSCARIUS, ALETRIS FARINOSA, ALFALFA, ALLIUM CEPA, ALLIUM SATIVUM, AMBROSIA ARTEMISIAEFOLIA, ARSENICUM ALBUM, ARTEMISIA VULGARIS, ARUNDO MAURITANICA, AVENA SATIVA, BELLADONNA, BELLIS PERRENIS, BOVISTA, BROMIUM, BRYONIA, CAFFEINUM, CALCAREA CARBONICA, CALLUNA VULGARIS, FLOS, CAPSICUM ANNUUM, CAT HAIR, CHAMOMILLA, CHELIDONIUM MAJUS, CHENOPODIUM ANTHELMINTICUM, CINNAMOMUM"},{"name":"Solvent/Small Ring Combination 9317","slug":"solvent/small-ring-combination","company":"Professional Complementary Health Formulas","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"SOLVENT/SMALL RING COMBINATION"},{"name":"ANIMAL ANTIGEN","slug":"feliscatushairbostaurushairbostaurusskingallusgallusfeathercanislupusfamiliarisskincanisfamiliarishairanasplatyrhynchosfeatheranseranserfeathercaviaporcellushaircaviaporcellusskinmesocricetusauratushairmesocricetusauratusskinsusscrofahairsusscrofaskinequuscaballushairequuscaballusdandermusmusculushairmusmusculuasskinoryctolaguscuniculusskinoryctolaguscuniculushairovisarieswholemeleagrisgallopavofeatherarsenictrioxideblattaorientalisstrychnosnux-vomicaseedphosphoruspulsatillasulfur","company":"Natural Creations, Inc.","advantage":"Same class (Non-Standardized Plant Allergenic Extract [EPC])","genericName":"FELISCATUSHAIR,BOSTAURUSHAIR,BOSTAURUSSKIN,GALLUSGALLUSFEATHER,CANISLUPUSFAMILIARISSKIN,CANISFAMILIARISHAIR,ANASPLATYRHYNCHOSFEATHER,ANSERANSERFEATHER,CAVIAPORCELLUSHAIR,CAVIAPORCELLUSSKIN,MESOCRICETUSAURATUSHAIR,MESOCRICETUSAURATUSSKIN,SUSSCROFAHAIR,SUSSCROFASKIN,EQUUSCABALLUSHAIR,EQUUSCABALLUSDANDER,MUSMUSCULUSHAIR,MUSMUSCULUASSKIN,ORYCTOLAGUSCUNICULUSSKIN,ORYCTOLAGUSCUNICULUSHAIR,OVISARIESWHOLE,MELEAGRISGALLOPAVOFEATHER,ARSENICTRIOXIDE,BLATTAORIENTALIS,STRYCHNOSNUX-VOMICASEED,PHOSPHORUS,PULSATILLA,SULFUR"}],"genericName":"sodium phosphate, dibasic, heptahydrate","indications":{"approved":[{"name":"To preserve purity avoid touching pellets with fingers","regulator":"FDA"},{"name":"Take apart from food or drinks","regulator":"FDA"},{"name":"To dissolve under your tongue before meals or as needed","regulator":"FDA"}]},"_drugCentral":{"patents":[{"number":"7687075","expires":"2028-06-22"}],"targets":[{"gene":"CA4","target":"Carbonic anhydrase 4","protein":"Carbonic anhydrase 4","activityType":"Ki","activityUnit":"","activityValue":5.01}],"atcCodes":["A06AD17","A06AG01","B05XA09","V03AG05"],"synonyms":["sodium phosphate, monobasic anhydrous","disodium phosphate","sodium phosphate","sodium phosphate, dibasic, heptahydrate","sodium phosphate, dibasic","sodium phosphate, dibasic anhydrous","sodium phosphate, monobasic, anhydrous"],"approvals":[{"date":"1983-05-10","orphan":false,"company":"HOSPIRA","regulator":"FDA"}],"properties":{},"drugClasses":["sodium phosphate"],"identifiers":{"NUI":"N0000146391","MMSL":"1109","NDDF":"001188","UNII":"SE337SVY37","VUID":"4018050","CHEBI":"CHEBI:37586","VANDF":"4017620","RXNORM":"221090","UMLSCUI":"C0074757","ChEMBL_ID":"CHEMBL1060","KEGG_DRUG":"D05869","DRUGBANK_ID":"DB09449","PUBCHEM_CID":"24243","SNOMEDCT_US":"71584004","SECONDARY_CAS_RN":"7782-85-6","MESH_SUPPLEMENTAL_RECORD_UI":"C018279"},"indications":[{"name":"Constipation","source":"DrugCentral","umlsCui":"C0009806","snomedId":14760008}],"formulations":[{"form":"CAPSULE","route":"ORAL","status":"UNAPPROVED DRUG OTHER","tradeName":"Vilamit MB"},{"form":"CAPSULE","route":"ORAL","status":"unapproved drug other","tradeName":"Uro-MP"},{"form":"CAPSULE","route":"ORAL","status":"unapproved drug other","tradeName":"UroAv-B"},{"form":"ENEMA","route":"RECTAL","status":"EXPORT ONLY","tradeName":"Fleet"},{"form":"ENEMA","route":"RECTAL","status":"EXPORT ONLY","tradeName":"Fleet for Children"},{"form":"ENEMA","route":"RECTAL","status":"Export 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