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The mechanism is non-specific and effective against a wide range of pathogens.","oneSentence":"Releases hypochlorous acid that disrupts microbial cell membranes and denatures proteins, providing broad-spectrum antimicrobial activity."},"_scrapedAt":"2026-03-28T05:29:08.676Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_claudeStub":{"ts":1779123029,"model":"claude-sonnet-4-5-20250929"},"competitors":[{"name":"Povidone-iodine","brand":"Betadine","company":null,"rationale":"Topical antiseptic for wound irrigation and surgical site preparation"},{"name":"Chlorhexidine gluconate","brand":"Hibiclens","company":null,"rationale":"Broad-spectrum antiseptic used for skin and wound disinfection"},{"name":"Hydrogen peroxide","brand":null,"company":null,"rationale":"Antiseptic solution for wound cleaning and irrigation"}],"description":"Sodium hypochlorite 2.5% irrigation is an antiseptic solution used primarily for wound irrigation and disinfection. It works by releasing hypochlorous acid, which has broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. The solution is commonly used in surgical settings and wound care management.","indications":{"approved":[{"status":"investigational","condition":"Wound irrigation and disinfection","patientPopulation":"Adult and paediatric patients requiring topical antisepsis"},{"status":"investigational","condition":"Surgical site preparation","patientPopulation":"Surgical patients requiring antimicrobial irrigation"}]},"trialDetails":[{"nctId":"NCT07041736","phase":"NA","title":"Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination","status":"RECRUITING","sponsor":"Al-Azhar University","startDate":"2025-08-03","conditions":"Post Operative Pain","enrollment":120},{"nctId":"NCT07453576","phase":"NA","title":"Effect Of Different Sodium Hypochlorite Concentrations On Intracanal Substance P, CGRP And Opiorphin Levels And Postoperative Pain During Root Canal Retreatment","status":"RECRUITING","sponsor":"KEZBAN MELTEM 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