{"id":"sodium-chlorure-0-9","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypernatremia (with excessive administration)"},{"rate":null,"effect":"Fluid overload (in renal impairment)"},{"rate":null,"effect":"Hyperchloremic acidosis (with prolonged high-volume infusion)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"This is a physiologic saline solution containing sodium and chloride ions in concentrations matching human blood plasma (0.9% w/v). It is used intravenously or topically to restore intravascular volume, maintain electrolyte balance, and prevent dehydration. As an isotonic solution, it does not cause cell lysis or crenation and is suitable for general fluid replacement in clinical settings.","oneSentence":"Sodium chloride 0.9% is an isotonic saline solution that replaces fluid and electrolytes to maintain osmotic balance and hydration.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:35:12.242Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Fluid and electrolyte replacement in dehydration"},{"name":"Intravenous hydration support"},{"name":"Wound irrigation and topical cleansing"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Sodium chlorure 0,9 %","genericName":"Sodium chlorure 0,9 %","companyName":"University Hospital, Rouen","companyId":"university-hospital-rouen","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sodium chloride 0.9% is an isotonic saline solution that replaces fluid and electrolytes to maintain osmotic balance and hydration. Used for Fluid and electrolyte replacement in dehydration, Intravenous hydration support, Wound irrigation and topical cleansing.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}