{"id":"sodium-chlorite","rwe":[{"pmid":"41806649","year":"2026","title":"Temperature-responsive microcapsule sachet enhances food preservation in cold chain through controlled ClO(2) release and multimodal action.","finding":"","journal":"Food chemistry","studyType":"Clinical Study"},{"pmid":"41778794","year":"2026","title":"Quantitative Approach for Simultaneous In Situ Profiling of Lignin, Cellulose, and Hemicellulose Using Confocal Raman Microscopy.","finding":"","journal":"Analytical chemistry","studyType":"Clinical Study"},{"pmid":"41610734","year":"2026","title":"Mouthrinses differentially rewire salivary virus-microbiome interaction dynamics in COVID-19 patients: A randomized controlled trial.","finding":"","journal":"Archives of oral biology","studyType":"Clinical Study"},{"pmid":"41519348","year":"2026","title":"Enhancing wood composite materials with formaldehyde-removing microcapsules featuring long-lasting, slow-release, and environmentally benign characteristics.","finding":"","journal":"International journal of biological macromolecules","studyType":"Clinical Study"},{"pmid":"41271060","year":"2025","title":"An innovative sodium carboxymethyl cellulose-based chlorine dioxide-releasing hydrogel incorporating α-cyclodextrin inclusion complexes and its potential for extending fruit shelf-life.","finding":"","journal":"International journal of biological macromolecules","studyType":"Clinical Study"}],"tags":[{"label":"sodium chlorite","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"D03AX11","category":"atc"},{"label":"Topical","category":"route"},{"label":"Liquid","category":"form"},{"label":"Powder","category":"form"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"textone","offLabel":[],"synonyms":["sodium chlorite","dioxychlor","textone"],"timeline":[],"approvals":[],"brandName":"Textone","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"sodium chlorite","explanation":"Think of Textone like a strong disinfectant that helps kill germs and bacteria in the body. When taken, it breaks down into chlorine dioxide, which then goes to work destroying the bad guys that can make us sick. This helps to reduce the severity of infections and promote healing.","oneSentence":"Textone works by releasing chlorine dioxide, a potent antimicrobial agent, which targets and kills pathogens.","technicalDetail":"Sodium chlorite is a prodrug that undergoes rapid conversion to chlorine dioxide in the body, which then exerts its antimicrobial effects through the oxidation of cellular components and disruption of cellular membranes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4784","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=sodium%20chlorite","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=sodium chlorite","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:40:20.012348","biosimilars":[],"competitors":[{"drugName":"dexpanthenol","drugSlug":"dexpanthenol","fdaApproval":"1953-02-20","relationship":"same-class"},{"drugName":"calcium pantothenate","drugSlug":"calcium-pantothenate","fdaApproval":"1993-12-29","relationship":"same-class"},{"drugName":"hyaluronic acid","drugSlug":"hyaluronic-acid","fdaApproval":"","relationship":"same-class"},{"drugName":"becaplermin","drugSlug":"becaplermin","fdaApproval":"1997-12-16","relationship":"same-class"},{"drugName":"trolamine","drugSlug":"trolamine","fdaApproval":"","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"sodium chlorite","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"dexpanthenol","brandName":"dexpanthenol","genericName":"dexpanthenol","approvalYear":"1953","relationship":"same-class"},{"drugId":"calcium-pantothenate","brandName":"calcium pantothenate","genericName":"calcium pantothenate","approvalYear":"1993","relationship":"same-class"},{"drugId":"hyaluronic-acid","brandName":"hyaluronic acid","genericName":"hyaluronic acid","approvalYear":"","relationship":"same-class"},{"drugId":"becaplermin","brandName":"becaplermin","genericName":"becaplermin","approvalYear":"1997","relationship":"same-class"},{"drugId":"trolamine","brandName":"trolamine","genericName":"trolamine","approvalYear":"","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT05258721","phase":"PHASE2","title":"Efficacy of ClōSYS® Sensitive Fluoride Toothpaste and ClōSYS® Sensitive Rinse Regimen on MGI, PI and BOP","status":"COMPLETED","sponsor":"Rowpar Pharmaceuticals, Inc.","startDate":"2021-07-06","conditions":["Gingivitis","Periodontitis"],"enrollment":60,"completionDate":"2022-10-31"},{"nctId":"NCT00947362","phase":"PHASE2,PHASE3","title":"Rationale for New Topical Anthroponotic Cutaneous Leishmaniasis (ACL) Treatment in Kabul","status":"COMPLETED","sponsor":"Waisenmedizin e. 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