{"id":"sodium-chloride-0-9-inj","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperchloremic acidosis (with large volume administration)"},{"rate":null,"effect":"Fluid overload / pulmonary edema (in susceptible patients)"},{"rate":null,"effect":"Hypernatremia (with excessive administration)"},{"rate":null,"effect":"Phlebitis at infusion site"}]},"_chembl":null,"_dailymed":{"setId":"69822a55-226c-f133-e3b8-2b5826667c5b","title":"LUMASON (SULFUR HEXAFLUORIDE) KIT LUMASON (SULFUR HEXAFLUORIDE) INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION [BRACCO DIAGNOSTICS INC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This solution contains sodium and chloride ions in physiologic concentrations (0.9% w/v) that match blood plasma osmolality, making it isotonic. It is used intravenously to restore intravascular volume, replace electrolytes lost through dehydration or bleeding, and serve as a vehicle for drug administration. The solution does not alter serum electrolyte concentrations when administered in normal quantities.","oneSentence":"Sodium chloride 0.9% is an isotonic saline solution that replaces fluid and electrolyte losses to maintain osmotic balance and hydration.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:08:29.868Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Fluid and electrolyte replacement in dehydration"},{"name":"Maintenance of intravascular volume in perioperative and critical care settings"},{"name":"Vehicle for intravenous drug administration"}]},"trialDetails":[{"nctId":"NCT05766904","phase":"PHASE3","title":"Efficacy Trial on Meningococcal B Vaccine for Preventing Gonorrhea Infections","status":"ACTIVE_NOT_RECRUITING","sponsor":"Chinese University of Hong Kong","startDate":"2023-05-04","conditions":"Gonorrhea, Sexually Transmitted Infection","enrollment":150},{"nctId":"NCT04608630","phase":"PHASE2","title":"Bone Loss Prevention 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Used for Fluid and electrolyte replacement in dehydration, Maintenance of intravascular volume in perioperative and critical care settings, Vehicle for intravenous drug administration.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":3,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}