{"id":"snp-acth-1-39-gel","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Skin irritation"},{"rate":"5-10%","effect":"Hypertension"},{"rate":"5-10%","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"SNP-ACTH (1-39) Gel works by binding to melanocortin receptors in the skin, which leads to increased production of cortisol. This increase in cortisol production can help to improve symptoms of adrenal insufficiency. The exact mechanism of action is not fully understood, but it is thought to be related to the stimulation of melanocortin receptors.","oneSentence":"SNP-ACTH (1-39) Gel is a synthetic peptide that mimics the action of adrenocorticotropic hormone (ACTH) to stimulate the production of cortisol.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:35:07.285Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Congenital adrenal hyperplasia"}]},"trialDetails":[{"nctId":"NCT05696613","phase":"PHASE3","title":"A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy","status":"RECRUITING","sponsor":"Cerium Pharmaceuticals, Inc.","startDate":"2023-03-13","conditions":"Primary Membranous Nephropathy","enrollment":148}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":218,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"SNP-ACTH (1-39) Gel","genericName":"SNP-ACTH (1-39) Gel","companyName":"Cerium Pharmaceuticals, Inc.","companyId":"cerium-pharmaceuticals-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"SNP-ACTH (1-39) Gel is a synthetic peptide that mimics the action of adrenocorticotropic hormone (ACTH) to stimulate the production of cortisol. Used for Congenital adrenal hyperplasia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}