{"id":"smoflipid-omegaven","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertriglyceridemia"},{"rate":null,"effect":"Infusion-related reactions"},{"rate":null,"effect":"Hepatic steatosis"},{"rate":null,"effect":"Thrombophlebitis at infusion site"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"SMOFlipid is a structured lipid emulsion containing soybean oil, medium-chain triglycerides, olive oil, and fish oil, designed to provide balanced essential fatty acids for parenteral nutrition. Omegaven is a pure fish oil (omega-3) emulsion that provides additional anti-inflammatory omega-3 polyunsaturated fatty acids. Together, they support metabolic needs while potentially reducing inflammatory complications in critically ill or post-operative patients requiring intravenous nutrition.","oneSentence":"SMOFlipid + Omegaven is a lipid emulsion combination that provides essential fatty acids and nutritional support for parenteral nutrition, with Omegaven supplying omega-3 fatty acids to modulate inflammatory responses.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:08:26.021Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Parenteral nutrition support in critically ill patients"},{"name":"Post-operative nutritional support"},{"name":"Patients unable to tolerate enteral nutrition"}]},"trialDetails":[{"nctId":"NCT03149653","phase":"PHASE4","title":"Crossover Study on the Effect of Omegaven in Combination With Different Lipid Emulsions in Home Parenteral Nutrition","status":"COMPLETED","sponsor":"General University Hospital, Prague","startDate":"2012-01-15","conditions":"Parenteral Nutrition","enrollment":24}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":23,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["SMOFlipid 20% Fresenius Kabi + Omegaven 10% Fresenius Kabi"],"phase":"marketed","status":"active","brandName":"SMOFlipid + Omegaven","genericName":"SMOFlipid + Omegaven","companyName":"General University Hospital, Prague","companyId":"general-university-hospital-prague","modality":"Small molecule","firstApprovalDate":"","aiSummary":"SMOFlipid + Omegaven is a lipid emulsion combination that provides essential fatty acids and nutritional support for parenteral nutrition, with Omegaven supplying omega-3 fatty acids to modulate inflammatory responses. Used for Parenteral nutrition support in critically ill patients, Post-operative nutritional support, Patients unable to tolerate enteral nutrition.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}