{"id":"smilon","safety":{"commonSideEffects":[{"rate":"1-5%","effect":"Edema"},{"rate":"1-5%","effect":"Dizziness"},{"rate":"1-5%","effect":"Headache"},{"rate":"1-5%","effect":"Nausea"},{"rate":"1-5%","effect":"Tachycardia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Smilon, also known as a dihydropyridine calcium channel blocker, acts by inhibiting the influx of calcium ions into smooth muscle cells, leading to vasodilation and a subsequent decrease in blood pressure. This mechanism is particularly effective in treating hypertension and angina pectoris.","oneSentence":"Smilon is a calcium channel blocker that works by relaxing blood vessels and reducing blood pressure.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:08:25.882Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertension"},{"name":"Angina pectoris"}]},"trialDetails":[{"nctId":"NCT01119924","phase":"PHASE4","title":"A Clinical Study for Assessment of the Efficacy and Safety of Mirtazapine (Smilon) in Depression Patients With Pain","status":"COMPLETED","sponsor":"Nang Kuang Pharmaceutical Co., Ltd.","startDate":"2009-12","conditions":"Depression, Pain","enrollment":30}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Smilon®","genericName":"Smilon®","companyName":"Nang Kuang Pharmaceutical Co., Ltd.","companyId":"nang-kuang-pharmaceutical-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Smilon is a calcium channel blocker that works by relaxing blood vessels and reducing blood pressure. Used for Hypertension, Angina pectoris.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}