{"id":"siv","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":{"setId":"75672079-589f-451a-bdbf-eaebcfcc80a9","title":"SIVEXTRO (TEDIZOLID PHOSPHATE) TABLET, FILM COATED SIVEXTRO (TEDIZOLID PHOSPHATE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [MERCK SHARP & DOHME LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"SIV vaccines are developed as research tools and potential preventive agents against Simian Immunodeficiency Virus, which is used in non-human primate models to study HIV pathogenesis and vaccine development. The inactivated formulation aims to stimulate both cellular and humoral immune responses without causing active infection. This vaccine platform has primarily been used in preclinical and research settings rather than for human therapeutic use.","oneSentence":"SIV is an inactivated Simian Immunodeficiency Virus vaccine candidate designed to elicit immune responses against SIV infection.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:08:27.162Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Research tool for studying SIV infection in non-human primates"}]},"trialDetails":[{"nctId":"NCT07365826","phase":"PHASE3","title":"A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age","status":"RECRUITING","sponsor":"Vaxcyte, Inc.","startDate":"2026-01-12","conditions":"Pneumococcal Vaccines","enrollment":1300},{"nctId":"NCT07156656","phase":"PHASE4","title":"Sivelestat Treatment for Postoperative Organ Protection in Type A Aortic Dissection","status":"NOT_YET_RECRUITING","sponsor":"Shanghai Zhongshan Hospital","startDate":"2025-09-01","conditions":"Type A Aortic Dissection, Organ Failure, Multiple","enrollment":236},{"nctId":"NCT06336824","phase":"PHASE3","title":"Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia","status":"RECRUITING","sponsor":"Clinical Research Centre, Malaysia","startDate":"2024-06-28","conditions":"Staphylococcus Aureus Bacteremia","enrollment":290},{"nctId":"NCT05155241","phase":"NA","title":"A Randomized Controlled Trial Evaluating an Online Intervention in Increasing Seasonal Influenza Vaccination Among Community Dwelling People Aged ≥65 Years","status":"COMPLETED","sponsor":"Chinese University of Hong Kong","startDate":"2021-12-01","conditions":"Vaccination Refusal","enrollment":396},{"nctId":"NCT04133584","phase":"PHASE4","title":"The Immunogenicity and Safety of the Vaccination of Inactivated Enterovirus 71 Vaccine and Seasonal Influenza Vaccine","status":"COMPLETED","sponsor":"Zhejiang Provincial Center for Disease Control and Prevention","startDate":"2019-09-16","conditions":"Seasonal Influenza, Hand, Foot and Mouth Disease","enrollment":1134},{"nctId":"NCT04629313","phase":"","title":"GCF Levels of IL-1Beta, MIP-1 Alfa and G-CSF in Gingivitis and Stage I-II-III-IV Periodontitis Patients","status":"COMPLETED","sponsor":"Uşak University","startDate":"2020-07-01","conditions":"Periodontitis","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":8139,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"SIV","genericName":"SIV","companyName":"Zhejiang Provincial Center for Disease Control and Prevention","companyId":"zhejiang-provincial-center-for-disease-control-and-prevention","modality":"Biologic","firstApprovalDate":"","aiSummary":"SIV is an inactivated Simian Immunodeficiency Virus vaccine candidate designed to elicit immune responses against SIV infection. Used for Research tool for studying SIV infection in non-human primates.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}