{"id":"sipv-dtap-mmr","safety":{"commonSideEffects":[{"rate":"10-30","effect":"Injection site pain, redness, or swelling"},{"rate":"5-15","effect":"Fever"},{"rate":"5-10","effect":"Rash"},{"rate":"5-10","effect":"Myalgia"},{"rate":"5-10","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"sIPV+DTaP+MMR is a multi-component vaccine combining inactivated poliovirus vaccine (sIPV), diphtheria-tetanus-acellular pertussis vaccine (DTaP), and measles-mumps-rubella vaccine (MMR). It stimulates humoral and cellular immune responses against these pathogens, inducing production of protective antibodies and memory B/T cells to prevent infection.","oneSentence":"This combination vaccine provides immunization against poliomyelitis, diphtheria, tetanus, pertussis, measles, mumps, and rubella through inactivated viral and bacterial antigens.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:08:19.006Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of poliomyelitis"},{"name":"Prevention of diphtheria"},{"name":"Prevention of tetanus"},{"name":"Prevention of pertussis"},{"name":"Prevention of measles"},{"name":"Prevention of mumps"},{"name":"Prevention of rubella"}]},"trialDetails":[{"nctId":"NCT06920069","phase":"PHASE4","title":"Study of Concomitant Administration of the sIPV and DTaP or MMR","status":"NOT_YET_RECRUITING","sponsor":"Institute of Medical Biology, Chinese Academy of Medical Sciences","startDate":"2025-05-15","conditions":"Polio, Diphteria, Tetanus and Pertussis, MMR Vaccine","enrollment":2640},{"nctId":"NCT06058429","phase":"","title":"Immunogenicity of After Primary Immunization and Booster Immunization of sIPV","status":"UNKNOWN","sponsor":"Sinovac Biotech Co., Ltd","startDate":"2023-08-16","conditions":"Polio","enrollment":233},{"nctId":"NCT05432141","phase":"PHASE4","title":"A Safety Study of Sabin Inactivated Poliovirus Vaccine in Infants","status":"COMPLETED","sponsor":"Sinovac Biotech Co., Ltd","startDate":"2022-06-13","conditions":"Poliomyelitis","enrollment":3200},{"nctId":"NCT04638985","phase":"PHASE4","title":"Evaluation of Immunogenicity and Safety of Combined Immunization of sIPV, DTaP and MMR","status":"UNKNOWN","sponsor":"China National Biotec Group Company Limited","startDate":"2020-11-13","conditions":"Vaccine","enrollment":600}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"sIPV+DTaP+MMR","genericName":"sIPV+DTaP+MMR","companyName":"China National Biotec Group Company Limited","companyId":"china-national-biotec-group-company-limited","modality":"Biologic","firstApprovalDate":"","aiSummary":"This combination vaccine provides immunization against poliomyelitis, diphtheria, tetanus, pertussis, measles, mumps, and rubella through inactivated viral and bacterial antigens. Used for Prevention of poliomyelitis, Prevention of diphtheria, Prevention of tetanus.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}