{"id":"sipv-batch-3","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (pain, redness, swelling)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability or fussiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"sIPV (Sabin inactivated poliovirus vaccine) is prepared from attenuated poliovirus strains that are chemically inactivated, making them unable to cause disease while retaining immunogenicity. When administered, it triggers both humoral (antibody) and cellular immune responses that provide protection against wild-type poliovirus infection. This vaccine is used as part of routine immunization programs to prevent poliomyelitis.","oneSentence":"sIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:08:15.896Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of poliomyelitis (polio) in infants and children"}]},"trialDetails":[{"nctId":"NCT04224519","phase":"PHASE4","title":"Consistency Study for Three Commercial Lots of Inactivated Poliomyelitis Vaccine Made From Sabin Strain","status":"COMPLETED","sponsor":"Institute of Medical Biology, Chinese Academy of Medical Sciences","startDate":"2018-04-15","conditions":"Poliomyelitis","enrollment":1200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"sIPV batch 3","genericName":"sIPV batch 3","companyName":"Institute of Medical Biology, Chinese Academy of Medical Sciences","companyId":"institute-of-medical-biology-chinese-academy-of-medical-sciences","modality":"Biologic","firstApprovalDate":"","aiSummary":"sIPV is an inactivated polio vaccine that stimulates the immune system to produce antibodies against poliovirus types 1, 2, and 3. Used for Prevention of poliomyelitis (polio) in infants and children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}