{"id":"sinupret-extract-coated-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Allergic reactions"},{"rate":null,"effect":"Headache"}]},"_chembl":{"chemblId":"CHEMBL2108766","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Sinupret contains a standardized extract of five medicinal plants (gentian root, primrose flowers, vervain herb, elderflower, and sorrel herb) that work synergistically to decrease mucus viscosity, enhance mucociliary clearance, and reduce inflammatory responses in the paranasal sinuses and upper respiratory tract. The extract promotes natural drainage of secretions and reduces swelling of the mucous membranes.","oneSentence":"Sinupret extract is a herbal combination that reduces inflammation and promotes drainage in the sinuses and respiratory tract.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:53:05.204Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute sinusitis"},{"name":"Chronic sinusitis"},{"name":"Rhinosinusitis"}]},"trialDetails":[{"nctId":"NCT02746042","phase":"PHASE3","title":"Sinupret Extract Coated Tablets in Chronic Rhinosinusitis","status":"COMPLETED","sponsor":"Bionorica SE","startDate":"2016-04-28","conditions":"Chronic Rhinosinusitis","enrollment":572},{"nctId":"NCT01146860","phase":"PHASE3","title":"Efficacy and Safety of a Herbal Medicinal Product (Dry Extract BNO 1016) in Patients With Acute Rhinosinusitis","status":"COMPLETED","sponsor":"Bionorica SE","startDate":"2010-01","conditions":"Acute Rhinosinusitis","enrollment":386}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Sinupret extract"],"phase":"phase_3","status":"active","brandName":"Sinupret extract coated tablets","genericName":"Sinupret extract coated tablets","companyName":"Bionorica SE","companyId":"bionorica-se","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sinupret extract is a herbal combination that reduces inflammation and promotes drainage in the sinuses and respiratory tract. Used for Acute sinusitis, Chronic sinusitis, Rhinosinusitis.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}