{"id":"silicone-gel-kelo-cort","safety":{"commonSideEffects":[{"rate":null,"effect":"Local skin irritation"},{"rate":null,"effect":"Contact dermatitis"},{"rate":null,"effect":"Skin atrophy (with prolonged corticosteroid use)"}]},"_chembl":{"chemblId":"CHEMBL4068611","moleculeType":"Small molecule","molecularWeight":"586.57"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Kelo-cort combines medical-grade silicone gel with a corticosteroid to address hypertrophic and keloid scars. The silicone component hydrates and flattens scar tissue while occluding the wound, while the corticosteroid reduces inflammation and collagen deposition. This dual mechanism targets both the physical appearance and underlying pathophysiology of abnormal scar formation.","oneSentence":"Silicone gel with integrated corticosteroid (likely hydrocortisone or similar) that provides topical anti-inflammatory and scar-reducing effects through moisture retention and steroid delivery to affected skin.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:34:32.210Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertrophic scars"},{"name":"Keloid scars"},{"name":"Post-surgical scars"}]},"trialDetails":[{"nctId":"NCT01861119","phase":"PHASE3","title":"Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars","status":"COMPLETED","sponsor":"CHA University","startDate":"2013-04-01","conditions":"Hypertrophic or Keloid Scars","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Silicone gel Kelo-cort™;","genericName":"Silicone gel Kelo-cort™;","companyName":"CHA University","companyId":"cha-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Silicone gel with integrated corticosteroid (likely hydrocortisone or similar) that provides topical anti-inflammatory and scar-reducing effects through moisture retention and steroid delivery to affected skin. Used for Hypertrophic scars, Keloid scars, Post-surgical scars.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}