{"id":"sid530-taxotere","safety":{"commonSideEffects":[{"rate":"High (> 40%)","effect":"Neutropenia"},{"rate":"High (> 30%)","effect":"Anemia"},{"rate":"Moderate (10-30%)","effect":"Thrombocytopenia"},{"rate":"Moderate (10-30%)","effect":"Fatigue"},{"rate":"Low (< 10%)","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This action prevents cancer cells from dividing and leads to cell death. Taxotere is a chemotherapeutic agent that targets rapidly dividing cells, making it effective against various types of cancer.","oneSentence":"Taxotere works by inhibiting microtubule formation in the mitotic spindle, resulting in cell cycle arrest at the G2/M phase and apoptosis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:34:39.104Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Adjuvant treatment of node-positive breast cancer"},{"name":"Locally advanced or metastatic breast cancer"},{"name":"Non-small cell lung cancer"},{"name":"Prostate cancer"}]},"trialDetails":[{"nctId":"NCT00931008","phase":"PHASE3","title":"Study to Evaluate SID 530 Compared to Taxotere","status":"COMPLETED","sponsor":"SK Chemicals Co., Ltd.","startDate":"2009-10","conditions":"Non-Small Cell Lung Cancer","enrollment":42}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"SID530, Taxotere","genericName":"SID530, Taxotere","companyName":"SK Chemicals Co., Ltd.","companyId":"sk-chemicals-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"SID530 is a small molecule that stabilizes tubulin, a protein involved in cell division. It is being studied in a clinical trial as a potential treatment for non-small cell lung cancer, compared to Taxotere, a known tubulin stabilizer.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}