{"id":"shuxuening-injection","safety":{"commonSideEffects":[{"rate":"null","effect":"Injection site reaction"}]},"_chembl":{"chemblId":"CHEMBL2108760","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The exact mechanism of action of Shuxuening Injection is not fully understood, but it is believed to work by modulating the immune system and reducing inflammation. This is thought to be achieved through the interaction of its various components with different molecular targets, although the specific pathways involved are not yet well characterized.","oneSentence":"Shuxuening Injection is a traditional Chinese medicine compound that has been shown to have anti-inflammatory and immunomodulatory effects.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:34:34.166Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of severe COVID-19"}]},"trialDetails":[{"nctId":"NCT06157502","phase":"PHASE3","title":"Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke (SHINY)","status":"RECRUITING","sponsor":"Beijing Tiantan Hospital","startDate":"2024-01-11","conditions":"Ischemic Stroke, Acute","enrollment":1380},{"nctId":"NCT06138353","phase":"PHASE2, PHASE3","title":"Shuxuening Injection for the Prevention of CVS in Patients With aSAH(SXN-CVS)","status":"RECRUITING","sponsor":"Xiaolin Chen, MD","startDate":"2024-01-24","conditions":"Subarachnoid Hemorrhage, Aneurysmal","enrollment":50},{"nctId":"NCT04950790","phase":"PHASE4","title":"Study on the Effectiveness and Safety of Shuxinin Injection in the Treatment of Acute Ischemic Stroke","status":"UNKNOWN","sponsor":"Peking University Third Hospital","startDate":"2018-04-01","conditions":"Acute Ischemic Stroke","enrollment":480},{"nctId":"NCT02259738","phase":"PHASE2","title":"Multi-modality MRI Study on Effect to Collateral Circulation and Blood Perfusion of Acute Cerebral Infarction by Human Urinary Kallidinogenase","status":"COMPLETED","sponsor":"XuanwuH 2","startDate":"2013-01","conditions":"Cerebral Infarction","enrollment":120},{"nctId":"NCT01752946","phase":"","title":"A Registry Study of Shuxuening Injection Used in Hospitals in China","status":"UNKNOWN","sponsor":"China Academy of Chinese Medical Sciences","startDate":"2012-10","conditions":"Coronary Disease, Intracranial Embolism, Stroke","enrollment":30000}],"_emaApprovals":[],"_faersSignals":[{"count":1,"reaction":"OEDEMA PERIPHERAL"}],"_approvalHistory":[],"publicationCount":65,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Shuxuening Injection","genericName":"Shuxuening Injection","companyName":"Beijing Tiantan Hospital","companyId":"beijing-tiantan-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Shuxuening Injection is a traditional Chinese medicine compound that has been shown to have anti-inflammatory and immunomodulatory effects. Used for Treatment of severe COVID-19.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}