{"id":"sham-subtenon-block","safety":{"commonSideEffects":[{"rate":null,"effect":"Eye irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This procedure is used to control pain and inflammation in the eye, and is often used in conjunction with other treatments. The exact mechanism of action is not well understood, but it is thought to involve the release of natural pain-relieving chemicals in the body. By mimicking the administration of a local anesthetic, the procedure can help to reduce pain and inflammation without the need for actual medication.","oneSentence":"Sham subtenon block is a procedure that mimics the administration of a local anesthetic to the eye, but does not actually administer any medication.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:34:19.402Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Control of pain and inflammation in the eye"}]},"trialDetails":[{"nctId":"NCT02282774","phase":"PHASE3","title":"Subtenon Block Combined With General Anesthesia for Vitreoretinal Surgery","status":"COMPLETED","sponsor":"King Saud University","startDate":"2013-12","conditions":"Subtenon Anesthesia","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Sham subtenon block","genericName":"Sham subtenon block","companyName":"King Saud University","companyId":"king-saud-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A sham subtenon block is a procedure used in clinical trials, specifically in the study of subtenon anesthesia for vitreoretinal surgery. The sham subtenon block typically involves the administration of either 2% lidocaine and 0.5% bupivacaine or a placebo, as part of a study to compare the effects of subtenon anesthesia with general anesthesia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}