{"id":"sham-bimatoprost-sr","safety":{"commonSideEffects":[{"rate":"null","effect":"Eyelash growth"}]},"_chembl":{"chemblId":"CHEMBL1200963","moleculeType":"Small molecule","molecularWeight":"415.57"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Prostaglandin analogs like Sham Bimatoprost SR work by binding to and activating the prostaglandin receptor, leading to increased outflow of aqueous humor from the eye and reduced intraocular pressure. This mechanism is similar to that of other prostaglandin analogs, such as bimatoprost, which is used to treat glaucoma and ocular hypertension.","oneSentence":"Sham Bimatoprost SR is a prostaglandin analog that mimics the action of prostaglandin F2-alpha.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:34:10.733Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of glaucoma and ocular hypertension"}]},"trialDetails":[{"nctId":"NCT04499248","phase":"PHASE1, PHASE2","title":"AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension","status":"RECRUITING","sponsor":"AbbVie","startDate":"2020-11-16","conditions":"Open-angle Glaucoma, Ocular Hypertension","enrollment":96},{"nctId":"NCT02507687","phase":"PHASE3","title":"Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension","status":"COMPLETED","sponsor":"AbbVie","startDate":"2015-08-27","conditions":"Glaucoma, Open-Angle, Ocular Hypertension","enrollment":240},{"nctId":"NCT02636946","phase":"PHASE3","title":"A Comparison of Bimatoprost SR to Selective Laser Trabeculoplasty in Patients With Open-Angle Glaucoma or Ocular Hypertension","status":"COMPLETED","sponsor":"Allergan","startDate":"2016-02-24","conditions":"Glaucoma, Open-Angle Ocular Hypertension","enrollment":144},{"nctId":"NCT02250651","phase":"PHASE3","title":"Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension","status":"COMPLETED","sponsor":"Allergan","startDate":"2014-12-15","conditions":"Glaucoma, Open-Angle, Ocular Hypertension","enrollment":528},{"nctId":"NCT02247804","phase":"PHASE3","title":"Efficacy and Safety Study of Bimatoprost Sustained-Release (SR) in Participants With Open-angle Glaucoma or Ocular Hypertension","status":"COMPLETED","sponsor":"Allergan","startDate":"2014-12-15","conditions":"Glaucoma, Open-Angle, Ocular Hypertension","enrollment":594}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Sham Bimatoprost SR","genericName":"Sham Bimatoprost SR","companyName":"AbbVie","companyId":"abbvie","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Sham Bimatoprost SR is a prostaglandin analog that mimics the action of prostaglandin F2-alpha. Used for Treatment of glaucoma and ocular hypertension.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":2},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}