{"id":"setiptiline","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Depressive disorder","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tecipul","offLabel":[],"synonyms":["tecipul","Org-8282","setiptiline","teciptilline","setiptiline maleate"],"timeline":[],"approvals":[],"brandName":"Tecipul","ecosystem":[{"indication":"Depressive disorder","otherDrugs":[{"name":"amitriptyline","slug":"amitriptyline","company":"Astrazeneca"},{"name":"amoxapine","slug":"amoxapine","company":"Lederle"},{"name":"bupropion","slug":"bupropion","company":"Glaxosmithkline"},{"name":"citalopram","slug":"citalopram","company":"Forest Labs"}],"globalPrevalence":280000000}],"mechanism":{"modality":"Small Molecule","explanation":"In simple terms, Tecipul is believed to help regulate the levels and activity of certain chemicals in the brain, such as serotonin and norepinephrine, which play a crucial role in mood regulation and emotional response.","oneSentence":"Tecipul is thought to work by modulating neurotransmitter activity in the brain.","technicalDetail":"The exact mechanism of action of Tecipul is unknown, but it is likely to involve the modulation of monoamine neurotransmitter systems, including serotonin and norepinephrine, through interaction with their respective receptors and transporters."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2438","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=SETIPTILINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:39:20.010773","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:48:51.663737+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[],"genericName":"setiptiline","indications":{"approved":[{"name":"Depressive disorder","source":"DrugCentral","snomedId":35489007,"regulator":"FDA","usPrevalence":21000000,"globalPrevalence":280000000,"prevalenceMethod":"curated","prevalenceSource":"WHO, 2023"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"008197","UNII":"7L38105Z6E","CHEBI":"CHEBI:135076","INN_ID":"5937","UMLSCUI":"C0069628","ChEMBL_ID":"CHEMBL2104895","KEGG_DRUG":"D02034","DRUGBANK_ID":"DB09304","PUBCHEM_CID":"5205","SECONDARY_CAS_RN":"85650-57-3","MESH_SUPPLEMENTAL_RECORD_UI":"C050605"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tecipul is a small molecule with the synonyms ORG 8282, SETIPTILINA, and SETIPTILINE.","enrichmentLevel":5,"visitCount":0,"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T08:48:51.663737+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}