{"id":"selective-nerve-root-block","safety":{"commonSideEffects":[{"rate":null,"effect":"Temporary increased pain"},{"rate":null,"effect":"Infection at injection site"},{"rate":null,"effect":"Bleeding or hematoma"},{"rate":null,"effect":"Dural puncture"},{"rate":null,"effect":"Transient neurological symptoms"}]},"_chembl":{"chemblId":"CHEMBL1201531","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The procedure involves fluoroscopic or ultrasound guidance to precisely target a specific nerve root exiting the spinal column. By injecting anesthetic (which provides immediate pain relief) and corticosteroid (which reduces inflammation), the procedure aims to alleviate radicular pain and improve function. This is a therapeutic intervention rather than a systemically-acting drug.","oneSentence":"A selective nerve root block is a minimally invasive injection procedure that delivers local anesthetic and/or corticosteroid directly to an inflamed nerve root to reduce pain and inflammation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:07:15.170Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Radicular pain from nerve root compression or inflammation"},{"name":"Cervical, thoracic, or lumbar radiculopathy"}]},"trialDetails":[{"nctId":"NCT07447271","phase":"NA","title":"Ultrasound Guided Cervical Selective Nerve Root Block Versus Fluoroscopic Guided Cervical Transforaminal Epidural Block","status":"ACTIVE_NOT_RECRUITING","sponsor":"Pusan National University Yangsan Hospital","startDate":"2025-12-22","conditions":"Cervical Radiculopathy","enrollment":330},{"nctId":"NCT06967363","phase":"","title":"Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)","status":"NOT_YET_RECRUITING","sponsor":"Peking University Third Hospital","startDate":"2025-05-15","conditions":"Chronic Low Back Pain (CLBP), Acute Low Back Pain, Low Back Pain","enrollment":360},{"nctId":"NCT00934284","phase":"","title":"Effectiveness Study of Physical Therapy As an Adjunct to a Lumbar Therapeutic Selective Nerve Root Block","status":"COMPLETED","sponsor":"University of Utah","startDate":"2006-01","conditions":"Sciatic Neuropathy, Radiculopathy, Intervertebral Disk Displacement","enrollment":44},{"nctId":"NCT06220591","phase":"NA","title":"Comparing Local Anesthetic Techniques for Clavicular Surgeries","status":"COMPLETED","sponsor":"Zagazig University","startDate":"2024-01-27","conditions":"Anesthesia, Local","enrollment":54},{"nctId":"NCT06143813","phase":"NA","title":"Precision Treatment of Lumbar Spine Surgery Through Advanced Nerve Root Blockade","status":"RECRUITING","sponsor":"University of Aarhus","startDate":"2023-11-09","conditions":"Radiculopathy Lumbar, Radiculopathy Sacral, Herniated Disc","enrollment":180},{"nctId":"NCT04451252","phase":"","title":"Predicting Response to Interventional Pain Management Techniques in Chronic Low Back Pain in a Prospective Cohort.","status":"COMPLETED","sponsor":"Santiago Garcia-Hernandez","startDate":"2019-10-02","conditions":"Low Back Pain, Pain Measurement, Chronic Pain","enrollment":400},{"nctId":"NCT05950321","phase":"NA","title":"Paramedian CESI vs Selective Nerve Root PRF for Lower Cervical Radicular Pain","status":"COMPLETED","sponsor":"Diskapi Teaching and Research Hospital","startDate":"2022-08-01","conditions":"Neck Pain, Cervical Radiculopathy","enrollment":60},{"nctId":"NCT05450926","phase":"NA","title":"Selective Cervical Root Block for Chronic Pain","status":"COMPLETED","sponsor":"Diskapi Teaching and Research Hospital","startDate":"2022-02-17","conditions":"Neck Pain","enrollment":60},{"nctId":"NCT03801356","phase":"PHASE4","title":"Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy","status":"TERMINATED","sponsor":"The Cleveland Clinic","startDate":"2018-08-23","conditions":"Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis","enrollment":11},{"nctId":"NCT05340179","phase":"NA","title":"Efficacy of Cervical Epidural Injection and Selective Nerve Root Block","status":"COMPLETED","sponsor":"Diskapi Teaching and Research Hospital","startDate":"2022-04-25","conditions":"Cervical Radiculopathy","enrollment":60},{"nctId":"NCT05521373","phase":"PHASE2, PHASE3","title":"Ultrasound-guided Versus Combined Ultrasound and Fluoroscopy-guided Cervical Selective Nerve Root Block for Lower Cervical Radiculopathy: Non-inferiority Randomized Controlled Study","status":"UNKNOWN","sponsor":"Mansoura University","startDate":"2022-05-01","conditions":"Cervical Pain","enrollment":68},{"nctId":"NCT05145530","phase":"PHASE2, PHASE3","title":"Selective Nerve Root Block With Ultrasound Guidance Improves Surgical Outcome of Selective Discectomy in Patients With Multilevel Cervical Disc Disease","status":"COMPLETED","sponsor":"Assiut University","startDate":"2017-08-10","conditions":"Selective Nerve Root Block, Selective Discectomy","enrollment":60},{"nctId":"NCT04964804","phase":"NA","title":"Comparative Study of Real-time Ultrasound-CT Fusion Imaging and Ultrasound-guided Selective Lumbar Nerve Root Block","status":"COMPLETED","sponsor":"Peking University Third Hospital","startDate":"2015-03-01","conditions":"Low Back Pain","enrollment":60},{"nctId":"NCT03919422","phase":"NA","title":"Paravertebral Block for Proximal Humeral Fracture Surgery","status":"COMPLETED","sponsor":"Shanghai 6th People's Hospital","startDate":"2019-05-05","conditions":"Proximal Humeral Fracture","enrollment":80},{"nctId":"NCT02761928","phase":"","title":"Investigation of Hypermobility, Biomarkers, and Pain Generators in Chronic Pain Patients","status":"TERMINATED","sponsor":"The University of Texas Health Science Center, Houston","startDate":"2016-01","conditions":"Low Back Pain, Mechanical, Spinal Stenosis, Nerve Root Disorder","enrollment":31}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":171,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Selective Nerve Root Block","genericName":"Selective Nerve Root Block","companyName":"The Cleveland Clinic","companyId":"the-cleveland-clinic","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A selective nerve root block is a minimally invasive injection procedure that delivers local anesthetic and/or corticosteroid directly to an inflamed nerve root to reduce pain and inflammation. Used for Radicular pain from nerve root compression or inflammation, Cervical, thoracic, or lumbar radiculopathy.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}