{"id":"secbutabarbital","brandName":"secbutabarbital","genericName":"secbutabarbital","companyId":"unknown","companyName":"","phase":"unknown","status":"active","modality":"","aliases":[],"developmentCodes":[],"firstApprovalDate":null,"firstApprovalCountry":null,"aiSummary":"Secbutabarbital is a small molecule barbiturate medication used as a prescription sleep aid and anxiety medication. It has a fast onset of effects and short duration of action, making it useful for treating severe insomnia, relieving general anxiety, and relieving anxiety before surgical procedures.","enrichmentLevel":3,"visitCount":0,"mechanism":{"target":"GABA-A receptor alpha-1/beta-2/gamma-2"},"administration":{},"safety":{"boxedWarnings":[],"safetySignals":[],"drugInteractions":[],"commonSideEffects":[],"contraindications":["Achalasia of esophagus","Acute exacerbation of asthma","Acute hepatitis","Aggressive behavior","Alcoholism","Anemia","Anemia due to enzyme deficiency","Anorexia nervosa","Arteriosclerotic vascular disease","Atony of colon","Benign prostatic hyperplasia","Bipolar disorder","Bladder outflow obstruction","Breastfeeding (mother)","Cardiomyopathy","Cardiovascular event risk","Cerebrovascular accident","Chronic heart failure","Chronic obstructive lung disease","Conduction disorder of the heart","Deficiency of glucose-6-phosphate dehydrogenase","Dependent drug abuse","Depressive disorder","Disease of liver","Disorder of autonomic nervous system","Disorder of cardiovascular system","Disorder of coronary artery","Feeling agitated","Fever greater than 100.4 Fahrenheit","Gastroesophageal reflux disease","Gilles de la Tourette's syndrome","Glaucoma","Glomerulonephritis","Hepatic coma","Hepatic encephalopathy","Hepatic failure","Hiatal hernia","Hyperactive behavior","Hyperammonemia","Hypertensive disorder","Hypertensive urgency","Hyperthyroidism","Hypovolemic shock","Kidney disease","Mania","Motor tic disorder","Myasthenia gravis","Myocardial infarction","Neutropenic disorder","Paralytic ileus","Porphyria","Pregnancy, function","Psychotic disorder","Pyloric obstruction","Respiratory insufficiency","Seizure disorder","Severe chronic ulcerative colitis","Sleep apnea","Sleep automatism","Structural disorder of heart","Substance abuse","Suicidal thoughts","Thrombocytopenic disorder","Toxic megacolon","Uremia","Visual impairment","Weight loss"],"specialPopulations":{},"discontinuationRates":[],"seriousAdverseEvents":[]},"trials":[],"indications":{"approved":[{"name":"Dysuria","diseaseId":"dysuria","approvalDate":"","lineOfTherapy":"","approvalCountry":"United States"},{"name":"Insomnia","diseaseId":"insomnia","approvalDate":"","lineOfTherapy":"","approvalCountry":"United States"},{"name":"Severe anxiety (panic)","diseaseId":"severe-anxiety-(panic)","approvalDate":"","lineOfTherapy":"","approvalCountry":"United States"},{"name":"Urinary Tract Irritation","diseaseId":"urinary-tract-irritation","approvalDate":"","lineOfTherapy":"","approvalCountry":"United States"}],"offLabel":[],"pipeline":[]},"commercial":null,"patents":[],"timeline":[],"rwe":[],"competitors":[],"ownershipHistory":[],"trialDetails":[],"genericFilers":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"labelChanges":[],"nice":null,"revenue":null,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":false,"indications":true,"safety":false,"trials":false,"score":1}}