{"id":"saw-palmetto-weeks-24-48","safety":{"commonSideEffects":[{"rate":"null","effect":"Gastrointestinal upset"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"The exact mechanism of saw palmetto's effects on BPH is unclear, but it may involve the inhibition of 5-alpha-reductase, an enzyme responsible for converting testosterone to DHT. This could potentially slow the growth of prostate tissue and alleviate symptoms of BPH.","oneSentence":"Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to benign prostatic hyperplasia (BPH).","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:52:53.209Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Benign prostatic hyperplasia (BPH)"}]},"trialDetails":[{"nctId":"NCT00603304","phase":"PHASE3","title":"Complementary and Alternative Medicine for Urological Symptoms(CAMUS)","status":"COMPLETED","sponsor":"University of Alabama at Birmingham","startDate":"2008-02","conditions":"Urological","enrollment":369}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Saw Palmetto - weeks 24 - 48","genericName":"Saw Palmetto - weeks 24 - 48","companyName":"University of Alabama at Birmingham","companyId":"university-of-alabama-at-birmingham","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Saw palmetto may inhibit the conversion of testosterone to dihydrotestosterone (DHT), a hormone linked to benign prostatic hyperplasia (BPH). Used for Benign prostatic hyperplasia (BPH).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}