{"id":"salvianolate-injection","safety":{"commonSideEffects":[{"rate":null,"effect":"Bleeding or hemorrhage"},{"rate":null,"effect":"Gastrointestinal discomfort"},{"rate":null,"effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Salvianolate contains multiple active compounds (salvianolic acids) that work through antiplatelet and anticoagulant mechanisms to enhance blood flow and reduce thrombotic events. It is believed to act on multiple pathways including inhibition of thromboxane synthesis and enhancement of prostacyclin, thereby improving tissue perfusion and reducing ischemic injury in cardiovascular and cerebrovascular conditions.","oneSentence":"Salvianolate is a water-soluble extract from Salvia miltiorrhiza that improves microcirculation and reduces blood viscosity by inhibiting platelet aggregation and promoting fibrinolysis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:06:40.554Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute ischemic stroke"},{"name":"Unstable angina pectoris"},{"name":"Myocardial infarction"}]},"trialDetails":[{"nctId":"NCT03306550","phase":"NA","title":"Mechanism of Drug-drug Interaction Between Salvianolate Injection and Aspirin","status":"UNKNOWN","sponsor":"Xiyuan Hospital of China Academy of Chinese Medical Sciences","startDate":"2017-10-10","conditions":"Angina, Stable","enrollment":18},{"nctId":"NCT03045562","phase":"PHASE4","title":"Effects of Salvianolate Injection on Myocardial Microcirculation in Patients With Acute STEMI After Primary PCI","status":"UNKNOWN","sponsor":"Green Valley Group of China","startDate":"2017-01-20","conditions":"STEMI - ST Elevation Myocardial Infarction","enrollment":536},{"nctId":"NCT03037047","phase":"PHASE4","title":"Efficacy and Safety of Salvianolate Injection in Elderly Patients With Unstable Angina Pectoris","status":"UNKNOWN","sponsor":"Green Valley Group of China","startDate":"2016-05-11","conditions":"Unstable Angina","enrollment":320},{"nctId":"NCT02694848","phase":"PHASE4","title":"Clinical Study of Combination Therapy for Angina of Coronary Heart Disease With Aspirin and Salvianolate Injection","status":"UNKNOWN","sponsor":"China Academy of Chinese Medical Sciences","startDate":"2016-02","conditions":"Angina","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":28,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Salvianolate"],"phase":"marketed","status":"active","brandName":"salvianolate injection","genericName":"salvianolate injection","companyName":"Green Valley Group of China","companyId":"green-valley-group-of-china","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Salvianolate is a water-soluble extract from Salvia miltiorrhiza that improves microcirculation and reduces blood viscosity by inhibiting platelet aggregation and promoting fibrinolysis. Used for Acute ischemic stroke, Unstable angina pectoris, Myocardial infarction.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":2,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}