{"id":"saline-solution-hypertonic","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperchloremic acidosis"},{"rate":null,"effect":"Hypernatremia"},{"rate":null,"effect":"Phlebitis at infusion site"},{"rate":null,"effect":"Rebound intracranial pressure elevation"},{"rate":null,"effect":"Acute kidney injury (with prolonged use)"}]},"_chembl":null,"_dailymed":{"setId":"464a97f8-784d-4e36-a458-6b628e2ca9cd","title":"HYPERTONIC SALINE SOLUTION 7.2% INJECTION, SOLUTION [ASPEN VETERINARY]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Hypertonic saline (typically 3%, 7%, or 23.4% NaCl) creates an osmotic gradient that pulls water from tissues into the bloodstream, thereby reducing brain swelling and intracranial pressure. It is commonly used in acute neurological emergencies to manage cerebral edema, traumatic brain injury, and increased intracranial pressure. 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