{"id":"sabia-plaster","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a transdermal plaster, Sabia provides sustained, controlled release of its active component across the skin barrier into systemic circulation, bypassing first-pass hepatic metabolism. This delivery method allows for prolonged therapeutic exposure with potentially improved tolerability and compliance compared to oral formulations. The specific molecular mechanism depends on the active ingredient contained within the patch formulation.","oneSentence":"Sabia plaster is a transdermal patch formulation that delivers an active pharmaceutical ingredient through the skin for systemic therapeutic effect.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:33:14.206Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[]},"trialDetails":[{"nctId":"NCT00970658","phase":"PHASE3","title":"Efficacy and Safety of Salonsip Compared to Sabiá Plaster","status":"UNKNOWN","sponsor":"Hisamitsu Farmaceutica do Brasil Ltda","startDate":"2009-12","conditions":"Contusions, Sprains, Myalgia","enrollment":70}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Sabia plaster","genericName":"Sabia plaster","companyName":"Hisamitsu Farmaceutica do Brasil Ltda","companyId":"hisamitsu-farmaceutica-do-brasil-ltda","modality":"Small molecule","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}