{"id":"rubidium-rb-82-chloride","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"V09GX04","category":"atc"},{"label":"Intravenous","category":"route"},{"label":"Injection","category":"form"},{"label":"Active","category":"status"},{"label":"Positron emission tomography","category":"indication"},{"label":"Bracco","category":"company"},{"label":"Approved 1980s","category":"decade"}],"phase":"marketed","safety":{"commonSideEffects":[],"specialPopulations":{"Lactation":"There is no information regarding the presence of Rb 82 chloride in human milk, the effects on the breastfed infant or the effects on milk production. Due to the short half-life of Rb 82 chloride (75 seconds), exposure of breastfed infant through breast milk can be minimized by temporary discontinuation of breastfeeding.","Pregnancy":"There are no data available on the use of rubidium Rb 82 chloride in pregnant women. Animal reproductive studies have not been conducted with rubidium Rb 82 chloride injection. However, all radiopharmaceuticals have the potential to cause fetal harm depending on the fetal stage of development and the magnitude of the radiation dose. If considering rubidium Rb 82 chloride injection administration to pregnant woman, inform the patient about the potential for adverse pregnancy outcomes based on the radiation dose from rubidium Rb 82 and the gestational timing of exposure.","Geriatric use":"In elderly patients with clinically important decrease in cardiac function, lengthen the delay between infusion and image acquisition. Observe for the possibility of fluid overload.","Paediatric use":"The safety and effectiveness of rubidium Rb 82 chloride injection in pediatric patients have not been established."}},"trials":[],"aliases":[],"company":"Bracco","patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=rubidium Rb-82 chloride","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T00:13:20.347453+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T00:13:26.296595+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=rubidium Rb-82 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N-13","slug":"ammonia-n-13","company":"Feinstein"},{"name":"Florbetapir F-18","slug":"florbetapir-f-18","company":"Avid Radiopharms Inc"},{"name":"Flutemetamol (18F)","slug":"flutemetamol-(18f)","company":"Ge Healthcare"},{"name":"Gallium Ga 68 dotatate","slug":"gallium-ga-68-dotatate","company":"Advanced Accelerator Applications Usa Inc"}],"globalPrevalence":null}],"mechanism":{"novelty":"First-in-class","modality":"Small Molecule","explanation":"","oneSentence":"","technicalDetail":"Rubidium Rb-82 chloride is a radioactive small molecule that undergoes positron emission decay, emitting positrons that interact with electrons in the body to produce gamma rays detectable by PET imaging."},"commercial":{"launchDate":"1989","_launchSource":"DrugCentral (FDA 1989-12-29, BRACCO)"},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5184","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=rubidium%20Rb-82%20chloride","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=rubidium Rb-82 chloride","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:37:09.439013","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T00:13:42.236937+00:00","fieldsConflicting":2,"overallConfidence":0.8},"biosimilars":[],"competitors":[{"drugName":"ammonia","drugSlug":"ammonia","fdaApproval":"","genericCount":28,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"rubidium rb-82 chloride","indications":{"approved":[{"name":"Positron emission 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Molecule","firstApprovalDate":"1989","aiSummary":"","enrichmentLevel":3,"visitCount":0,"regulatoryByCountry":[{"country_code":"US","regulator":"FDA","status":"approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":""},{"country_code":"SA","regulator":"SFDA","status":"likely_approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":null},{"country_code":"AE","regulator":"MOH","status":"likely_approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":null},{"country_code":"KR","regulator":"MFDS","status":"likely_approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":null},{"country_code":"IL","regulator":"MOH","status":"likely_approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":null},{"country_code":"SG","regulator":"HSA","status":"likely_approved","approval_date":"1989-12-29T00:00:00.000Z","mah":"BRACCO","brand_name_local":null,"application_number":null},{"country_code":"CA","regulator":"Health 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