{"id":"rotavin-liquid-formulation","safety":{"commonSideEffects":[{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability"}]},"_chembl":{"chemblId":"CHEMBL2108930","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains weakened rotavirus strains that replicate in the intestinal tract, triggering both humoral (antibody) and cell-mediated immune responses without causing severe disease. This primes the immune system to recognize and neutralize wild-type rotavirus upon natural exposure, preventing or reducing the severity of rotavirus gastroenteritis.","oneSentence":"ROTAVIN is a live attenuated rotavirus vaccine that stimulates the immune system to produce antibodies and cellular immunity against rotavirus infection.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:32:52.671Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of rotavirus gastroenteritis in infants and young children"}]},"trialDetails":[{"nctId":"NCT03703336","phase":"PHASE3","title":"Phase III Study of Liquid Formulation of ROTAVIN","status":"COMPLETED","sponsor":"Center for Research and Production of Vaccines and Biologicals, Vietnam","startDate":"2019-03-16","conditions":"Diarrhea, Diarrhea Rotavirus","enrollment":825}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"ROTAVIN (liquid formulation)","genericName":"ROTAVIN (liquid formulation)","companyName":"Center for Research and Production of Vaccines and Biologicals, Vietnam","companyId":"center-for-research-and-production-of-vaccines-and-biologicals-vietnam","modality":"Biologic","firstApprovalDate":"","aiSummary":"ROTAVIN is a live attenuated rotavirus vaccine that stimulates the immune system to produce antibodies and cellular immunity against rotavirus infection. Used for Prevention of rotavirus gastroenteritis in infants and young children.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}