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This combination is used to extend the duration and improve the quality of regional anesthesia.","oneSentence":"Ropivacaine blocks sodium channels to provide local anesthesia, while clonidine enhances analgesia by activating alpha-2 adrenergic receptors.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:05:55.923Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Regional anesthesia and analgesia (peripheral nerve blocks, epidural anesthesia)"}]},"trialDetails":[{"nctId":"NCT07377630","phase":"PHASE4","title":"Intrathecal MoRphine Versus Transabdominal Plane Block (TAP) Block for AnalGesic Management in Elective Caesarean Section","status":"NOT_YET_RECRUITING","sponsor":"Istituto Giannina Gaslini","startDate":"2026-03-01","conditions":"Pregnancy, Cesarean Section, Neuroaxial Analgesia Procedures","enrollment":100},{"nctId":"NCT07350252","phase":"PHASE4","title":"Combination of Nerve Blocks and Local Infiltration Analgesia in Knee 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