{"id":"romurtide","rwe":[{"pmid":"18832728","year":"2008","title":"Differential effects of GM-CSF and G-CSF on infiltration of dendritic cells during early left ventricular remodeling after myocardial infarction.","finding":"","journal":"Journal of immunology (Baltimore, Md. : 1950)","studyType":"Clinical Study"},{"pmid":"18786661","year":"2008","title":"Solid-state cultivation of Grifola frondosa (Dicks: Fr) S.F. Gray biomass and immunostimulatory effects of fungal intra- and extracellular beta-polysaccharides.","finding":"","journal":"New biotechnology","studyType":"Clinical Study"},{"pmid":"15464336","year":"2004","title":"Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction.","finding":"","journal":"Journal of the American College of Cardiology","studyType":"Clinical Study"},{"pmid":"12770506","year":"2003","title":"Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides.","finding":"","journal":"Journal of biotechnology","studyType":"Clinical Study"},{"pmid":"11367521","year":"2001","title":"Induction of tumor necrosis factor-alpha in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide.","finding":"","journal":"International immunopharmacology","studyType":"Clinical Study"}],"tags":[{"label":"romurtide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Adjuvants, Immunologic","category":"pharmacology"},{"label":"Immunologic Factors","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"nopia","offLabel":[],"synonyms":["romurtide","muroctasin","muroctasine","nopia"],"timeline":[],"approvals":[],"brandName":"Nopia","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"romurtide","explanation":"Think of it like a key fitting into a lock - Nopia is the key that helps to unlock a specific response in the body. This response can help to treat certain conditions by reducing inflammation or other symptoms. By binding to its target receptor, Nopia helps to send a signal that tells the body to take a specific action.","oneSentence":"Nopia works by binding to and activating a specific receptor, which helps to regulate the body's response to certain stimuli.","technicalDetail":"Nopia is a small molecule agonist that selectively binds to and activates the receptor, leading to a downstream signaling cascade that results in the desired therapeutic effect."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/2400","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ROMURTIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T15:36:25.716901","biosimilars":[],"competitors":[],"genericName":"romurtide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"SUP956TPT6","CHEBI":"CHEBI:32106","INN_ID":"6406","UMLSCUI":"C0067246","ChEMBL_ID":"CHEMBL1908331","KEGG_DRUG":"D01722","PUBCHEM_CID":"6917906","MESH_SUPPLEMENTAL_RECORD_UI":"C036866"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":27,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2008 Oct 15","pmid":"18832728","title":"Differential effects of GM-CSF and G-CSF on infiltration of dendritic cells during early left ventricular remodeling after myocardial infarction.","journal":"Journal of immunology (Baltimore, Md. : 1950)"},{"date":"2008 Oct-Dec","pmid":"18786661","title":"Solid-state cultivation of Grifola frondosa (Dicks: Fr) S.F. Gray biomass and immunostimulatory effects of fungal intra- and extracellular beta-polysaccharides.","journal":"New biotechnology"},{"date":"2004 Oct 6","pmid":"15464336","title":"Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction.","journal":"Journal of the American College of Cardiology"},{"date":"2003 Jun 12","pmid":"12770506","title":"Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides.","journal":"Journal of biotechnology"},{"date":"2001 Jan","pmid":"11367521","title":"Induction of tumor necrosis factor-alpha in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide.","journal":"International immunopharmacology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Nopia is a small molecule modality. It is also known by the synonyms Romurtida and Romurtide.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}