{"id":"rohto-r-hydra","safety":{"commonSideEffects":[{"rate":null,"effect":"Temporary blurred vision"},{"rate":null,"effect":"Eye irritation"},{"rate":null,"effect":"Allergic reaction (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This over-the-counter eye drop product works as an artificial tear substitute, delivering hydrating agents and lubricants to the cornea and conjunctiva. It helps reduce symptoms of dry eye disease by maintaining tear film stability and protecting the eye surface from further desiccation and irritation.","oneSentence":"Rohto Hydra is an ophthalmic lubricant that provides moisture and relief to dry eyes by forming a protective hydrating layer on the ocular surface.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:05:42.663Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye syndrome / Dry eye disease"}]},"trialDetails":[{"nctId":"NCT02985827","phase":"PHASE4","title":"Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra)","status":"COMPLETED","sponsor":"ORA, Inc.","startDate":"2015-12","conditions":"Dry Eye","enrollment":48}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Rohto Hydra"],"phase":"marketed","status":"active","brandName":"Rohto (r) Hydra","genericName":"Rohto (r) Hydra","companyName":"ORA, Inc.","companyId":"ora-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rohto Hydra is an ophthalmic lubricant that provides moisture and relief to dry eyes by forming a protective hydrating layer on the ocular surface. Used for Dry eye syndrome / Dry eye disease.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}