{"id":"rocuronium-dosing","safety":{"commonSideEffects":[{"rate":null,"effect":"Prolonged neuromuscular blockade"},{"rate":null,"effect":"Histamine release (flushing, hypotension, tachycardia)"},{"rate":null,"effect":"Anaphylaxis"},{"rate":null,"effect":"Postoperative residual curarization"}]},"_chembl":{"chemblId":"CHEMBL1200648","moleculeType":"Small molecule","molecularWeight":"609.69"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Rocuronium is a non-depolarizing (competitive) neuromuscular blocker that antagonizes acetylcholine at the motor endplate by occupying nicotinic acetylcholine receptors without activating them. This prevents depolarization and muscle contraction, producing paralysis. 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Used for Facilitation of endotracheal intubation during anesthesia induction, Maintenance of neuromuscular blockade during general anesthesia and mechanical ventilation.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}