{"id":"rinderon-dp-betamethasone-dipropionate","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Skin atrophy"},{"rate":"5-10%","effect":"Hypopigmentation"},{"rate":"5-10%","effect":"Irritation"}]},"_chembl":{"chemblId":"CHEMBL3138708","moleculeType":"Small molecule","molecularWeight":"504.60"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Betamethasone dipropionate, the active ingredient in Rinderon, is a synthetic corticosteroid that exerts its anti-inflammatory effects by inhibiting the transcription of inflammatory genes. This results in a decrease in the production of pro-inflammatory cytokines, such as IL-1, IL-6, and TNF-alpha, which are involved in the inflammatory response. By reducing inflammation, Rinderon helps to alleviate symptoms associated with various skin conditions.","oneSentence":"Rinderon inhibits the body's inflammatory response by suppressing the production of various pro-inflammatory cytokines.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:32:12.355Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Severe skin conditions such as psoriasis, eczema, and dermatitis"}]},"trialDetails":[{"nctId":"NCT01422434","phase":"PHASE3","title":"LEO 90105 Ointment in Japanese Subjects With Psoriasis","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2011-07","conditions":"Psoriasis","enrollment":676}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Rinderon® - DP = betamethasone dipropionate","genericName":"Rinderon® - DP = betamethasone dipropionate","companyName":"LEO Pharma","companyId":"leo-pharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rinderon inhibits the body's inflammatory response by suppressing the production of various pro-inflammatory cytokines. Used for Severe skin conditions such as psoriasis, eczema, and dermatitis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}