{"id":"rikkunshi-to","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal side effects"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It is a Kampo formula composed of several herbal ingredients, including ginger, ginseng, and licorice root, which work together to soothe the digestive system and alleviate symptoms of nausea and vomiting.","oneSentence":"Rikkunshi-to is a traditional Japanese medicine used to treat gastrointestinal disorders.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:32:11.244Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Gastrointestinal disorders, including nausea and vomiting"}]},"trialDetails":[{"nctId":"NCT07285707","phase":"NA","title":"Acupuncture and Chinese Herbal Medicine for Long COVID","status":"RECRUITING","sponsor":"Southern California University of Health Sciences","startDate":"2025-09-10","conditions":"Long COVID","enrollment":10},{"nctId":"NCT06482671","phase":"PHASE3","title":"Primary Care dySpEpsia rikkuNshiTo","status":"RECRUITING","sponsor":"Universitaire Ziekenhuizen KU Leuven","startDate":"2024-10-01","conditions":"Dyspepsia and Other Specified Disorders of Function of Stomach, Postprandial Distress Syndrome","enrollment":100},{"nctId":"NCT05066841","phase":"NA","title":"Chinese Herbal Medicine Formula Combined With Inhaled Corticosteroids for the Treatment of Mild to Persistent Asthma in Children","status":"UNKNOWN","sponsor":"China Medical University Hospital","startDate":"2021-09-25","conditions":"Childhood Asthma","enrollment":86},{"nctId":"NCT04388358","phase":"NA","title":"Traditional Chinese Medicine for the Treatment of Perennial Allergic Rhinitis on Gut Microbiota and Immune-modulation","status":"COMPLETED","sponsor":"Chang Gung Memorial Hospital","startDate":"2019-09-03","conditions":"Allergic Rhinitis","enrollment":33},{"nctId":"NCT03856294","phase":"PHASE2","title":"The Effect of Rikkunshito on Gastric Accommodation and Nutrient Volume Tolerance in Functional Dyspepsia","status":"COMPLETED","sponsor":"Universitaire Ziekenhuizen KU Leuven","startDate":"2015-12","conditions":"Dyspepsia","enrollment":34},{"nctId":"NCT02037776","phase":"PHASE4","title":"The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia","status":"COMPLETED","sponsor":"Osaka City University","startDate":"2014-04-03","conditions":"Functional Dyspepsia","enrollment":128},{"nctId":"NCT02179580","phase":"PHASE2, PHASE3","title":"A Study of Xiang-Sha-Liu-Jun-Zi-Tang in Patients With Irritable Bowel Syndrome","status":"UNKNOWN","sponsor":"China Medical University Hospital","startDate":"2014-06","conditions":"Irritable Bowel Syndrome","enrollment":80}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":29,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Rikkunshi-to","genericName":"Rikkunshi-to","companyName":"Universitaire Ziekenhuizen KU Leuven","companyId":"universitaire-ziekenhuizen-ku-leuven","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rikkunshi-to is a treatment being studied for various conditions, including dyspepsia, long COVID, and allergic rhinitis, in clinical trials. However, according to ChEMBL, Rikkunshi-to is actually a vaccine component, specifically a polysaccharide conjugated to Tetanus toxoid, used as an antigen.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}