{"id":"rhgh-norditropine-simple-xx","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Hyperglycemia"},{"rate":null,"effect":"Carpal tunnel syndrome"},{"rate":null,"effect":"Fluid retention"},{"rate":null,"effect":"Arthralgia"}]},"_chembl":{"chemblId":"CHEMBL4114427","moleculeType":"Small molecule","molecularWeight":"490.61"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"rhGH is a recombinant form of endogenous human growth hormone that activates the growth hormone receptor on target tissues, promoting linear growth in children, increasing lean body mass, and enhancing metabolic function. It stimulates insulin-like growth factor 1 (IGF-1) production, which mediates many of its anabolic and growth-promoting effects.","oneSentence":"Recombinant human growth hormone (rhGH) binds to growth hormone receptors to stimulate growth, metabolism, and protein synthesis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:04:53.583Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Growth hormone deficiency in children"},{"name":"Growth hormone deficiency in adults"},{"name":"Short stature in children born small for gestational age"},{"name":"Turner syndrome"}]},"trialDetails":[{"nctId":"NCT00597480","phase":"PHASE4","title":"Study of Growth-promoting and Metabolic Effects of Growth Hormone (rhGH)","status":"TERMINATED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2008-01","conditions":"Small for Gestational Age","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"rhGH norditropine simple Xx","genericName":"rhGH norditropine simple Xx","companyName":"Assistance Publique - Hôpitaux de Paris","companyId":"assistance-publique-h-pitaux-de-paris","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Recombinant human growth hormone (rhGH) binds to growth hormone receptors to stimulate growth, metabolism, and protein synthesis. Used for Growth hormone deficiency in children, Growth hormone deficiency in adults, Short stature in children born small for gestational age.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}