{"id":"retaine","safety":{"commonSideEffects":[{"rate":null,"effect":"Blurred vision"},{"rate":null,"effect":"Eye irritation"},{"rate":null,"effect":"Mild ocular discomfort"}]},"_chembl":null,"_dailymed":{"setId":"06f57d46-96c7-4093-84aa-874ff4b2131d","title":"RETAINE MGD (MINERAL OIL) EMULSION [OCUSOFT LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Retaine contains a lipid-based emulsion (castor oil and other oils) that mimics the lipid layer of the tear film, helping to stabilize tears and reduce evaporative dry eye. By restoring tear film composition and reducing water loss from the ocular surface, it provides symptomatic relief and protects corneal and conjunctival tissues in dry eye disease.","oneSentence":"Retaine is an ophthalmic emulsion that lubricates and protects the ocular surface by supplementing natural tears and reducing evaporation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:04:55.840Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Dry eye disease / keratoconjunctivitis sicca"}]},"trialDetails":[{"nctId":"NCT02139033","phase":"PHASE4","title":"A Phase 4 Study Investigating the Efficacy of Retaine™ in Managing Signs and Symptoms Associated With Dry Eye Syndrome","status":"COMPLETED","sponsor":"Ocusoft, Inc.","startDate":"2014-05","conditions":"Keratoconjunctivitis Sicca","enrollment":42}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Retaine™","genericName":"Retaine™","companyName":"Ocusoft, Inc.","companyId":"ocusoft-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Retaine is an ophthalmic emulsion that lubricates and protects the ocular surface by supplementing natural tears and reducing evaporation. Used for Dry eye disease / keratoconjunctivitis sicca.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}