{"id":"restrictive-platelet-transfusion","safety":{"commonSideEffects":[{"rate":"unknown","effect":"Thrombotic events"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This approach aims to balance the benefits of platelet transfusion in preventing bleeding complications with the risks of thrombotic events. By restricting the number of platelets transfused, clinicians can minimize the risk of adverse outcomes while still providing necessary support to patients with bleeding disorders.","oneSentence":"Restrictive platelet transfusion involves limiting the number of platelets transfused to patients to prevent complications associated with excessive platelet accumulation.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:31:56.218Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Thrombocytopenia for patients undergoing chemotherapy"}]},"trialDetails":[{"nctId":"NCT06676904","phase":"NA","title":"Neonatal Platelet Transfusion Threshold Trial","status":"RECRUITING","sponsor":"NICHD Neonatal Research Network","startDate":"2025-06-13","conditions":"Thrombocytopenia, Neonatal, Platelet Transfusion","enrollment":2433},{"nctId":"NCT06553833","phase":"","title":"Outcomes of Patient Blood Management in Patients Undergoing Major Surgery","status":"COMPLETED","sponsor":"Helios Klinik Gotha/Ohrdruf","startDate":"2024-09-01","conditions":"Major Surgery","enrollment":25979},{"nctId":"NCT05667805","phase":"PHASE4","title":"Coagulation in Cirrhosis","status":"RECRUITING","sponsor":"Medical University of Vienna","startDate":"2023-01-19","conditions":"Liver Cirrhosis","enrollment":400},{"nctId":"NCT06345417","phase":"","title":"Outcomes of Patient Blood Management in Severely Anemic Patients","status":"NOT_YET_RECRUITING","sponsor":"Helios Klinik Gotha/Ohrdruf","startDate":"2024-04-01","conditions":"Severe Anemia","enrollment":20000},{"nctId":"NCT03217370","phase":"NA","title":"Study on Patient Blood Management in Haematological Patients","status":"SUSPENDED","sponsor":"Universitaire Ziekenhuizen KU Leuven","startDate":"2017-08-01","conditions":"Blood Transfusion, Haematology","enrollment":700},{"nctId":"NCT03444077","phase":"NA","title":"Impact of a Prehospital Identification of Trauma Patients in Need for Damage Control Resuscitation.","status":"UNKNOWN","sponsor":"University of Liege","startDate":"2018-07","conditions":"Trauma, Coagulopathy, Hemorrhage","enrollment":400},{"nctId":"NCT03022253","phase":"PHASE3","title":"Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates","status":"COMPLETED","sponsor":"Post Graduate Institute of Medical Education and Research, Chandigarh","startDate":"2016-03","conditions":"Patent Ductus Arteriosus","enrollment":44},{"nctId":"NCT02311985","phase":"NA","title":"Comparison of Three Transfusion Strategies for Central Venous Catheterization in Cirrhotics: A Randomized Clinical Trial","status":"TERMINATED","sponsor":"Hospital Israelita Albert Einstein","startDate":"2014-09","conditions":"Liver Cirrhosis","enrollment":57}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":18,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Restrictive platelet transfusion","genericName":"Restrictive platelet transfusion","companyName":"Post Graduate Institute of Medical Education and Research, Chandigarh","companyId":"post-graduate-institute-of-medical-education-and-research-chandigarh","modality":"Biologic","firstApprovalDate":"","aiSummary":"Restrictive platelet transfusion involves limiting the number of platelets transfused to patients to prevent complications associated with excessive platelet accumulation. Used for Thrombocytopenia for patients undergoing chemotherapy.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}